[NMR paper] Palladium in the Chemical Synthesis and Modification of Proteins
Palladium in the Chemical Synthesis and Modification of Proteins
The field of site-specific modification of proteins has drawn significant attention in recent years owing to its importance in various research areas such as the development of novel therapeutics and understanding the biochemical and cellular behaviors of proteins. The presence of a large number of reactive functional groups in the protein of interest and in the cellular environment renders modification at a specific site a highly challenging task. With the development of sophisticated chemical methodologies it is now...
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08-07-2017 07:31 PM
[NMR paper] Palladium in Chemical Protein Synthesis and Modifications
Palladium in Chemical Protein Synthesis and Modifications
The field of site-specific modification of proteins has drawn significant attentions in recent years owing to its high importance in various research areas such as the development of novel therapeutics and understanding the biochemical and cellular behaviors of proteins. The presence of a large number of reactive functional groups in the protein of interest and in the cellular environment renders the particular modification at a specific site a highly challenging task. However, with the development of sophisticated...
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04-07-2017 02:01 AM
N–H···N Hydrogen Bonds Involving Histidine Imidazole Nitrogen Atoms: A New Structural Role for Histidine Residues in Proteins
N–H···N Hydrogen Bonds Involving Histidine Imidazole Nitrogen Atoms: A New Structural Role for Histidine Residues in Proteins
http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/bichaw/0/bichaw.ahead-of-print/acs.biochem.6b00253/20160628/images/medium/bi-2016-00253v_0008.gif
Biochemistry
DOI: 10.1021/acs.biochem.6b00253
http://feeds.feedburner.com/~ff/acs/bichaw?d=yIl2AUoC8zA
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06-29-2016 09:52 AM
[NMR paper] Mechanism of Tau-Promoted Microtubule Assembly As Probed by NMR Spectroscopy.
Mechanism of Tau-Promoted Microtubule Assembly As Probed by NMR Spectroscopy.
Mechanism of Tau-Promoted Microtubule Assembly As Probed by NMR Spectroscopy.
J Am Chem Soc. 2014 Aug 27;
Authors: Gigant B, Landrieu I, Fauquant C, Barbier P, Huvent I, Wieruszeski JM, Knossow M, Lippens G
Abstract
Determining the molecular mechanism of the neuronal Tau protein in the tubulin heterodimer assembly has been a challenge owing to the dynamic character of the complex and the large size of microtubules. We use here defined constructs...
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08-28-2014 10:09 AM
Nmr characterization of self-association domains promoted by interactions with lc8 hub protein
NMR CHARACTERIZATION OF SELF-ASSOCIATION DOMAINS PROMOTED BY INTERACTIONS WITH LC8 HUB PROTEIN
Publication date: February 2014
Source:Computational and Structural Biotechnology Journal, Volume 9, Issue 14</br>
Author(s): Elisar Barbar , Afua Nyarko</br>
Most proteins in interaction networks have a small number of partners, while a few, called hubs, participate in a large number of interactions and play a central role in cell homeostasis. One highly conserved hub is a protein called LC8 that was originally identified as an essential component of the multi-subunit...
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08-11-2014 02:21 PM
The structure and dynamic properties of the complete histidine phosphotransfer domain of the chemotaxis specific histidine autokinase CheA from Thermotoga maritima
The structure and dynamic properties of the complete histidine phosphotransfer domain of the chemotaxis specific histidine autokinase CheA from Thermotoga maritima
Abstract The bacterial histidine autokinase CheA contains a histidine phosphotransfer (Hpt) domain that accepts a phosphate from the catalytic domain and donates the phosphate to either target response regulator protein, CheY or CheB. The Hpt domain forms a helix-bundle structure with a conserved four-helix bundle motif and a variable fifth helix. Observation of two nearly equally populated conformations in the crystal...
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09-30-2011 08:01 PM
[NMR paper] Synthesis and NMR solution structure of an alpha-helical hairpin stapled with two dis
Synthesis and NMR solution structure of an alpha-helical hairpin stapled with two disulfide bridges.
Related Articles Synthesis and NMR solution structure of an alpha-helical hairpin stapled with two disulfide bridges.
Protein Sci. 2000 May;9(5):942-55
Authors: Barthe P, Rochette S, Vita C, Roumestand C
Helical coiled-coils and bundles are some of the most common structural motifs found in proteins. Design and synthesis of alpha-helical motifs may provide interesting scaffolds that can be useful as host structures to display functional sites,...
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11-18-2010 09:15 PM
[NMR paper] 1H NMR studies of reactions of copper complexes with human blood plasma and urine.
1H NMR studies of reactions of copper complexes with human blood plasma and urine.
Related Articles 1H NMR studies of reactions of copper complexes with human blood plasma and urine.
Biochem Pharmacol. 1992 Jan 22;43(2):137-45
Authors: Bligh SW, Boyle HA, McEwen AB, Sadler PJ, Woodham RH
Reactions of the copper complexes Cu(II)Cl2, 2-, and + (where DIPS is 3,5-diisopropylsalicylate and DMP is 2,9-dimethylphenanthroline) with human blood plasma and urine have been studied by 500 MHz 1H NMR spectroscopy, and CD spectroscopy has been used to...
Intracellular Reactions Promoted by Bis(histidine) Miniproteins Stapled Using Palladium(II) Complexes
Linear Mode
