NMR paper Improving Assessment of Lipoprotein Profile in Type 1 Diabetes by 1H NMR Spectroscopy.

		BioNMR > Educational resources > Journal club
[NMR paper] Improving Assessment of Lipoprotein Profile in Type 1 Diabetes by 1H NMR Spectroscopy.

Webservers

NMR processing:

MDD

NMR assignment:

Backbone:

Side-chains:

NOEs:

Structure from NMR restraints:

Ab initio:

Fragment-based:

Rosetta-NMR (Robetta)

Template-based:

GeNMR

I-TASSER

Refinement:

Amber

Structure from chemical shifts:

Fragment-based:

Homology-based:

Torsion angles from chemical shifts:

Preditor

TALOS

Promega- Proline

Secondary structure from chemical shifts:

CSI (via RCI server)

TALOS

MICS caps, β-turns

d2D

PECAN

Flexibility from chemical shifts:

RCI

Interactions from chemical shifts:

HADDOCK

Chemical shifts re-referencing:

NMR model quality:

NOEs, other restraints:

Chemical shifts:

RDCs:

Pseudocontact shifts:

Protein geomtery:

SAVES2 or SAVES4

Quality Control Check

NMR spectrum prediction:

FANDAS

MestReS

V-NMR

Flexibility from structure:

Backbone S2

Methyl S2

B-factor

Molecular dynamics:

Gromacs

Amber

Antechamber

Chemical shifts prediction:

From structure:

Shiftx2

Sparta+

Camshift

CH3shift- Methyl

ArShift- Aromatic

ShiftS

Proshift

PPM

CheShift-2- Cα

From sequence:

Shifty

Camcoil

Poulsen_rc_CS

Disordered proteins:

MAXOCC

Format conversion & validation:

CCPN

From NMR-STAR 3.1

Validate NMR-STAR 3.1

NMR sample preparation:

Protein disorder:

DisMeta

Protein solubility:

Isotope labeling:

Solid-state NMR:

Thread Tools

Search this Thread

Rate Thread

Display Modes

05-12-2016, 09:30 PM

nmrlearner

Senior Member

Join Date: Jan 2005

Posts: 23,777

Points: 193,617, Level: 100

Level up: 0%, 0 Points needed

Activity: 50.7%

Last Achievements

Award-Showcase

NMR Credits: 0

NMR Points: 193,617

Downloads: 0

Uploads: 0

Improving Assessment of Lipoprotein Profile in Type 1 Diabetes by 1H NMR Spectroscopy.

Related Articles Improving Assessment of Lipoprotein Profile in Type 1 Diabetes by 1H NMR Spectroscopy.

PLoS One. 2015;10(8):e0136348

Authors: Brugnara L, Mallol R, Ribalta J, Vinaixa M, Murillo S, Casserras T, Guardiola M, Vallvé JC, Kalko SG, Correig X, Novials A

Abstract
Patients with type 1 diabetes (T1D) present increased risk of cardiovascular disease (CVD). The aim of this study is to improve the assessment of lipoprotein profile in patients with T1D by using a robust developed method 1H nuclear magnetic resonance spectroscopy (1H NMR), for further correlation with clinical factors associated to CVD. Thirty patients with T1D and 30 non-diabetes control (CT) subjects, matched for gender, age, body composition (DXA, BMI, waist/hip ratio), regular physical activity levels and cardiorespiratory capacity (VO2peak), were analyzed. Dietary records and routine lipids were assessed. Serum lipoprotein particle subfractions, particle sizes, and cholesterol and triglycerides subfractions were analyzed by 1H NMR. It was evidenced that subjects with T1D presented lower concentrations of small LDL cholesterol, medium VLDL particles, large VLDL triglycerides, and total triglycerides as compared to CT subjects. Women with T1D presented a positive association with HDL size (p

Did you find this post helpful?

Similar Threads
Thread	Thread Starter	Forum	Replies	Last Post
Lipoprotein insulin resistance measurement predicts future diabetes risk - Healio <img alt="" height="1" width="1"> Lipoprotein insulin resistance measurement predicts future diabetes risk Healio â??The lipoprotein insulin resistance (LPIR) score is a composite of six lipoprotein parameters measured by nuclear magnetic resonance spectroscopy that reflects the lipoprotein derangements of insulin resistance, which may be apparent months or years ... Lipoprotein insulin resistance measurement predicts future diabetes risk - Healio More...	nmrlearner	Online News	0	04-22-2016 08:45 PM
Lipoprotein profile in PCOS may lead to insight on CV risk - Healio Lipoprotein profile in PCOS may lead to insight on CV risk - Healio <img alt="" height="1" width="1"> Lipoprotein profile in PCOS may lead to insight on CV risk Healio Nuclear magnetic resonance (NMR) spectroscopy was used to measure LDL particle size and number. Compared with controls, participants with PCOS had higher LDL particle numbers (P = .032). High-sensitivity C-reactive protein (P = .006) and waist-to-hip ... Read here	nmrlearner	Online News	0	09-22-2015 06:40 PM
[NMR paper] Apolipoprotein-defined and NMR lipoprotein subclasses in the veterans affairs diabetes trial. Apolipoprotein-defined and NMR lipoprotein subclasses in the veterans affairs diabetes trial. http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--linkinghub.elsevier.com-ihub-images-PubMedLink.gif Related Articles Apolipoprotein-defined and NMR lipoprotein subclasses in the veterans affairs diabetes trial. J Diabetes Complications. 2013 Nov-Dec;27(6):627-32 Authors: Azar M, Lyons TJ, Alaupovic P, Stoner JA, Quiroga C, Kaufman DG, Lopes-Virella M, Klein RL, Jenkins AJ, VADT Study Group Abstract	nmrlearner	Journal club	0	07-02-2014 02:37 PM
[NMR paper] (1)H-NMR spectroscopy revealed Mycobacterium tuberculosis caused abnormal serum metabolic profile of cattle. (1)H-NMR spectroscopy revealed Mycobacterium tuberculosis caused abnormal serum metabolic profile of cattle. http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--www.plosone.org-images-pone_120x30.png http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--www.pubmedcentral.nih.gov-corehtml-pmc-pmcgifs-pubmed-pmc.gif Related Articles (1)H-NMR spectroscopy revealed Mycobacterium tuberculosis caused abnormal serum metabolic profile of cattle. PLoS One. 2013;8(9):e74507 Authors: Chen Y, Wu J, Tu L, Xiong X, Hu X,...	nmrlearner	Journal club	0	05-13-2014 03:11 PM
[NMR paper] Improving the quality of protein structures derived by NMR spectroscopy. Improving the quality of protein structures derived by NMR spectroscopy. Related Articles Improving the quality of protein structures derived by NMR spectroscopy. J Biomol NMR. 2002 Mar;22(3):281-9 Authors: Spronk CA, Linge JP, Hilbers CW, Vuister GW Biomolecular structures provide the basis for many studies in several research areas such as homology modelling, structure-based drug design and functional genomics. It is an important prerequisite that the structure is reliable in terms of accurate description of the experimental data, and in...	nmrlearner	Journal club	0	11-24-2010 08:49 PM
[NMR paper] Assessment of cholesteryl ester transfer protein function in lipoprotein mixtures by Assessment of cholesteryl ester transfer protein function in lipoprotein mixtures by 1H NMR spectroscopy. http://www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--www3.interscience.wiley.com-aboutus-images-wiley_interscience_pubmed_logo_120x27.gif Related Articles Assessment of cholesteryl ester transfer protein function in lipoprotein mixtures by 1H NMR spectroscopy. NMR Biomed. 1997 Oct;10(7):303-8 Authors: Korhonen A, Ala-Korpela M, Liinamaa MJ, Jokisaari J, KesÃ¤niemi YA, Savolainen MJ Studies of cholesteryl ester transfer protein (CETP)...	nmrlearner	Journal club	0	08-22-2010 05:08 PM
Lipoprotein size, concentrations associated with incident type 2 diabetes - Endocrine Lipoprotein size, concentrations associated with incident type 2 diabetes - Endocrine Today <img alt="" height="1" width="1" /> Lipoprotein size, concentrations associated with incident type 2 diabetes Endocrine Today Mora and colleagues used nuclear magnetic resonance spectroscopy on a small blood specimen to measure baseline lipoprotein particle size and concentration, ...	nmrlearner	Online News	0	08-15-2010 03:09 AM
[NMR tweet] Study links Type 2 diabetes to lipoprotein particles - Related ...: Researchers using Study links Type 2 diabetes to lipoprotein particles - Related ...: Researchers using nuclear magnetic resonance s... http://bit.ly/biBcoL Source: Twitter	nmrlearner	Twitter NMR	0	08-14-2010 02:48 PM

« Previous Thread | Next Thread »

Posting Rules
You may not post new threads You may not post replies You may not post attachments You may not edit your posts BB code is On Smilies are On [IMG] code is On HTML code is On Trackbacks are Off Pingbacks are Off Refbacks are Off