ConformationalDynamics of a Seven Transmembrane HelicalProtein Anabaena Sensory RhodopsinProbed by Solid-State NMR
ConformationalDynamics of a Seven Transmembrane HelicalProtein Anabaena Sensory RhodopsinProbed by Solid-State NMR
Daryl B. Good, Shenlin Wang, Meaghan E. Ward, Jochem Struppe, Leonid S. Brown, Jo?zef R. Lewandowski and Vladimir Ladizhansky
http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/jacsat/0/jacsat.ahead-of-print/ja411633w/aop/images/medium/ja-2013-11633w_0011.gif
Journal of the American Chemical Society
DOI: 10.1021/ja411633w
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[NMR paper] Unraveling a phosphorylation event in a folded protein by NMR spectroscopy: phosphorylation of the Pin1 WW domain by PKA.
Unraveling a phosphorylation event in a folded protein by NMR spectroscopy: phosphorylation of the Pin1 WW domain by PKA.
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J Biomol NMR. 2013 Mar 2;
Authors: Smet-Nocca C, Launay H, Wieruszeski JM, Lippens G, Landrieu I
Abstract
The Pin1 protein plays a critical role in the functional regulation of the hyperphosphorylated neuronal Tau protein in Alzheimer's disease and is by itself regulated by phosphorylation. We have...
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Cervical cancer: First 3-D image of an HPV oncoprotein - Medical Xpress
Cervical cancer: First 3-D image of an HPV oncoprotein - Medical Xpress
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Cervical cancer: First 3-D image of an HPV oncoprotein
Medical Xpress
Success depended on two factors: the development of methods for isolating protein E6 as well as the use of nuclear magnetic resonance (NMR) and crystallography techniques. Having dealt with various aggregation and purification problems, the researchers ...
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Understanding small-molecule binding to MDM2: insights into structural effects of isoindolinone inhibitors from NMR spectroscopy.
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Chem Biol Drug Des. 2011 May;77(5):301-8
Authors: Riedinger C, Noble ME, Wright DJ, Mulks F, Hardcastle IR, Endicott JA, McDonnell JM
The interaction between murine double minute (MDM2) and p53 is a major target in anticancer drug design. Several potent compound series, including the nutlins...
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Authors: Fry DC, Emerson SD, Palme S, Vu BT, Liu CM, Podlaski F
MDM2 is a regulator of cell growth processes that acts by binding to the tumor suppressor protein p53 and ultimately restraining its activity. While inactivation of p53 by mutation is commonly observed in human cancers, a substantial percentage of tumors express wild type p53. In many of...
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Towards a structural understanding of the smallest known oncoprotein: Investigation o
Towards a structural understanding of the smallest known oncoprotein: Investigation of the Bovine Papillomavirus E5 protein using solution-state NMR.
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The homo-dimeric E5 protein from Bovine Papillomavirus activates the platelet-derived growth factor ? receptor through transmembrane (TM)...
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Dissection of the basic subdomain of the c-Jun oncoprotein: a structural analysis of two peptide fragments by CD, Fourier-transform infrared and NMR.
http://www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--www3.interscience.wiley.com-aboutus-images-wiley_interscience_pubmed_logo_FREE_120x27.gif Related Articles Dissection of the basic subdomain of the c-Jun oncoprotein: a structural analysis of two peptide fragments by CD, Fourier-transform infrared and NMR.
Eur J Biochem. 1996 Feb 1;235(3):699-712
Authors: Krebs D, Dahmani B, Monnot M, Mauffret O,...
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[NMR paper] The basic subdomain of the c-Jun oncoprotein. A joint CD, Fourier-transform infrared
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http://www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--www3.interscience.wiley.com-aboutus-images-wiley_interscience_pubmed_logo_FREE_120x27.gif Related Articles The basic subdomain of the c-Jun oncoprotein. A joint CD, Fourier-transform infrared and NMR study.
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Impact of Ser17 Phosphorylation on the ConformationalDynamics of the Oncoprotein MDM2
Linear Mode
