INEPT- and HMQC-based pulse sequences are widely used to transfer polarization between heteronuclei, particularly in biomolecular spectroscopy: they are easy to setup and involve low power deposition. Still, these short-pulse polarization transfers schemes are challenged by fast solvent chemical exchange. An alternative to improve these heteronuclear transfers is J-driven cross polarization (J-CP), which transfers polarization by spin-locking the coupled spins under Hartmann-Hahn conditions....
TRACT revisited: an algebraic solution for determining overall rotational correlation times from cross-correlated relaxation rates
TRACT revisited: an algebraic solution for determining overall rotational correlation times from cross-correlated relaxation rates
Abstract
Accurate rotational correlation times ( \({\tau }_{\text{c}}\) ) are critical for quantitative analysis of fast timescale NMR dynamics. As molecular weights increase, the classic derivation of \({\tau }_{c}\) using transverse and longitudinal relaxation rates...
nmrlearner
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09-04-2021 10:34 AM
[ASAP] The Incorporation of Labile Protons into Multidimensional NMR Analyses: Glycan Structures Revisited
The Incorporation of Labile Protons into Multidimensional NMR Analyses: Glycan Structures Revisited
Mihajlo Novakovic, Marcos D. Battistel, Hugo F. Azurmendi, Maria-Grazia Concilio, Daro?n I. Freedberg, and Lucio Frydman
https://pubs.acs.org/na101/home/literatum/publisher/achs/journals/content/jacsat/0/jacsat.ahead-of-print/jacs.1c04512/20210604/images/medium/ja1c04512_0008.gif
Journal of the American Chemical Society
DOI: 10.1021/jacs.1c04512
http://feeds.feedburner.com/~r/acs/jacsat/~4/H2MJ7chRt4g
nmrlearner
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06-05-2021 09:30 AM
[NMR paper] The Incorporation of Labile Protons into Multidimensional NMR Analyses: Glycan Structures Revisited
The Incorporation of Labile Protons into Multidimensional NMR Analyses: Glycan Structures Revisited
Glycan structures are often stabilized by a repertoire of hydrogen-bonded donor/acceptor groups, revealing longer-lived structures that could represent biologically relevant conformations. NMR provides unique data on these hydrogen-bonded networks from multidimensional experiments detecting cross-peaks resulting from through-bond (TOCSY) or through-space (NOESY) interactions. However, fast OH/H(2)O exchange, and the spectral proximity among these NMR resonances, hamper the use of glycans'...
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06-05-2021 09:30 AM
Heteronuclear Cross-Relaxation under Solid-State Dynamic Nuclear Polarization #DNPNMR
From The DNP-NMR Blog:
Heteronuclear Cross-Relaxation under Solid-State Dynamic Nuclear Polarization #DNPNMR
p.p1 {margin: 0.0px 0.0px 0.0px 36.0px; text-indent: -36.0px; font: 12.0px Helvetica}
Daube, D., et al., Heteronuclear Cross-Relaxation under Solid-State Dynamic Nuclear Polarization. J. Am. Chem. Soc., 2016. 138(51): p. 16572-16575.
http://dx.doi.org/10.1021/jacs.6b08683
nmrlearner
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03-07-2017 08:21 AM
Heteronuclear DNP of protons and deuterons with TEMPOL #DNPNMR
From The DNP-NMR Blog:
Heteronuclear DNP of protons and deuterons with TEMPOL #DNPNMR
Kaminker, I., et al., Heteronuclear DNP of protons and deuterons with TEMPOL. Phys Chem Chem Phys, 2016. 18(16): p. 11017-41.
https://www.ncbi.nlm.nih.gov/pubmed/27047995
nmrlearner
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09-22-2016 10:41 PM
[Question from NMRWiki Q&A forum] OH, NH, SH Labile protons in water nmr
OH, NH, SH Labile protons in water nmr
Hello all,
Just to mirror Craig Grimmer's question about labile protons in non-aqueous solvents, does anyone know of any good articles dealing with labile proton behavior in water?
Thanks,
nmrlearner
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03-11-2015 09:59 PM
Dual-band Selective Double Cross Polarization for Heteronuclear Polarization Transfer between Dilute Spins in Solid-State MAS NMR
Dual-band Selective Double Cross Polarization for Heteronuclear Polarization Transfer between Dilute Spins in Solid-State MAS NMR
Publication year: 2012
Source:Journal of Magnetic Resonance</br>
Zhengfeng Zhang, Yimin Miao, Xiaoli Liu, Jun Yang, Conggang Li, Feng Deng, Riqiang Fu</br>
A sinusoidal modulation scheme is described for selective heteronuclear polarization transfer between two dilute spins in double cross polarization magic-angle-spinning nuclear magnetic resonance spectroscopy. During the second N->C cross polarization, the 13C RF amplitude is...
nmrlearner
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03-09-2012 09:16 AM
Dual-band Selective Double Cross Polarization for Heteronuclear Polarization Transfer between Dilute Spins in Solid-State MAS NMR
Dual-band Selective Double Cross Polarization for Heteronuclear Polarization Transfer between Dilute Spins in Solid-State MAS NMR
Publication year: 2012
Source: Journal of Magnetic Resonance, Available online 5 March 2012</br>
Zhengfeng*Zhang, Yimin*Miao, Xiaoli*Liu, Jun*Yang, Conggang*Li, ...</br>
A sinusoidal modulation scheme is described for selective heteronuclear polarization transfer between two dilute spins in double cross polarization magic-angle-spinning nuclear magnetic resonance spectroscopy. During the second N->C cross polarization, theC RF amplitude is modulated...
Heteronuclear transfers from labile protons in biomolecular NMR: Cross polarization, revisited
Linear Mode
