Neural network folds proteins a million times faster than its competitors - Chemistry World
Neural network folds proteins a million times faster than its competitors Chemistry WorldDespite knowing next to nothing about chemistry or biology, a neural network can make a good stab at one of the toughest problems in biochemistry – predicting ...
Neural network folds proteins a million times faster than its competitors - Chemistry World
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05-09-2019 05:55 AM
De novo protein structure determination from near-atomic-resolution cryo-EM maps - Nature.com
De novo protein structure determination from near-atomic-resolution cryo-EM maps - Nature.com
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De novo protein structure determination from near-atomic-resolution cryo-EM maps
Nature.com
Despite these developments, little progress has been made in de novo model building into near-atomic-resolution cryo-EM density maps. Structural interpretation of cryo-EM maps typically starts with fitting an atomic X-ray or NMR structure into the map5.
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02-24-2015 02:48 PM
[NMR paper] Protein Structural Information Derived from NMR Chemical Shift with the Neural Network Program TALOS-N.
Protein Structural Information Derived from NMR Chemical Shift with the Neural Network Program TALOS-N.
Protein Structural Information Derived from NMR Chemical Shift with the Neural Network Program TALOS-N.
Methods Mol Biol. 2015;1260:17-32
Authors: Shen Y, Bax A
Abstract
Chemical shifts are obtained at the first stage of any protein structural study by NMR spectroscopy. Chemical shifts are known to be impacted by a wide range of structural factors, and the artificial neural network based TALOS-N program has been trained to...
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12-17-2014 09:43 PM
[NMR paper] Practical use of chemical shift databases for protein solid-state NMR: 2D chemical shift maps and amino-acid assignment with secondary-structure information.
Practical use of chemical shift databases for protein solid-state NMR: 2D chemical shift maps and amino-acid assignment with secondary-structure information.
Practical use of chemical shift databases for protein solid-state NMR: 2D chemical shift maps and amino-acid assignment with secondary-structure information.
J Biomol NMR. 2013 Apr 28;
Authors: Fritzsching KJ, Yang Y, Schmidt-Rohr K, Hong M
Abstract
We introduce a Python-based program that utilizes the large database of (13)C and (15)N chemical shifts in the Biological Magnetic...
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04-30-2013 10:21 PM
[NMR paper] Probability-based protein secondary structure identification using combined NMR chemi
Probability-based protein secondary structure identification using combined NMR chemical-shift data.
Related Articles Probability-based protein secondary structure identification using combined NMR chemical-shift data.
Protein Sci. 2002 Apr;11(4):852-61
Authors: Wang Y, Jardetzky O
For a long time, NMR chemical shifts have been used to identify protein secondary structures. Currently, this is accomplished through comparing the observed (1)H(alpha), (13)C(alpha), (13)C(beta), or (13)C' chemical shifts with the random coil values. Here, we...
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11-24-2010 08:49 PM
[NMR paper] RESCUE: an artificial neural network tool for the NMR spectral assignment of proteins
RESCUE: an artificial neural network tool for the NMR spectral assignment of proteins.
Related Articles RESCUE: an artificial neural network tool for the NMR spectral assignment of proteins.
J Biomol NMR. 1999 Sep;15(1):15-26
Authors: Pons JL, Delsuc MA
The assignment of the 1H spectrum of a protein or a polypeptide is the prerequisite for advanced NMR studies. We present here an assignment tool based on the artificial neural network technology, which determines the type of the amino acid from the chemical shift values observed in the 1H...
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11-18-2010 08:31 PM
NMR assignments and the identification of the secondary structure of the anti-retrovi
NMR assignments and the identification of the secondary structure of the anti-retroviral cytidine deaminase.
Related Articles NMR assignments and the identification of the secondary structure of the anti-retroviral cytidine deaminase.
Nucleic Acids Symp Ser (Oxf). 2008;(52):183-4
Authors: Furukawa A, Nagata T, Habu Y, Sugiyama R, Hayashi F, Yokoyama S, Takaku H, Katahira M
APOBEC3G (apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3G) is known to have a role in intrinsic cellular immunity against human immunodeficiency virus type1...
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11-17-2010 05:49 PM
[NMR paper] Using neural network predicted secondary structure information in automatic protein N
Using neural network predicted secondary structure information in automatic protein NMR assignment.
Related Articles Using neural network predicted secondary structure information in automatic protein NMR assignment.
J Chem Inf Comput Sci. 1997 Nov-Dec;37(6):1086-94
Authors: Choy WY, Sanctuary BC, Zhu G
In CAPRI, an automated NMR assignment software package that was developed in our laboratory, both chemical shift values and coupling topologies of spin patterns are used in a procedure for amino acids recognition. By using a knowledge base of...
Haruspex: A Neural Network for the Automatic Identification of Oligonucleotides and Protein Secondary Structure in Cryo-EM Maps
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