A General Mechanism for the Propagation of MutationalEffects in Proteins

		BioNMR > Educational resources > Journal club
A General Mechanism for the Propagation of MutationalEffects in Proteins

Webservers

NMR processing:

MDD

NMR assignment:

Backbone:

Side-chains:

NOEs:

Structure from NMR restraints:

Ab initio:

Fragment-based:

Rosetta-NMR (Robetta)

Template-based:

GeNMR

I-TASSER

Refinement:

Amber

Structure from chemical shifts:

Fragment-based:

Homology-based:

Torsion angles from chemical shifts:

Preditor

TALOS

Promega- Proline

Secondary structure from chemical shifts:

CSI (via RCI server)

TALOS

MICS caps, β-turns

d2D

PECAN

Flexibility from chemical shifts:

RCI

Interactions from chemical shifts:

HADDOCK

Chemical shifts re-referencing:

NMR model quality:

NOEs, other restraints:

Chemical shifts:

RDCs:

Pseudocontact shifts:

Protein geomtery:

SAVES2 or SAVES4

Quality Control Check

NMR spectrum prediction:

FANDAS

MestReS

V-NMR

Flexibility from structure:

Backbone S2

Methyl S2

B-factor

Molecular dynamics:

Gromacs

Amber

Antechamber

Chemical shifts prediction:

From structure:

Shiftx2

Sparta+

Camshift

CH3shift- Methyl

ArShift- Aromatic

ShiftS

Proshift

PPM

CheShift-2- Cα

From sequence:

Shifty

Camcoil

Poulsen_rc_CS

Disordered proteins:

MAXOCC

Format conversion & validation:

CCPN

From NMR-STAR 3.1

Validate NMR-STAR 3.1

NMR sample preparation:

Protein disorder:

DisMeta

Protein solubility:

Isotope labeling:

Solid-state NMR:

Thread Tools

Search this Thread

Rate Thread

Display Modes

12-28-2016, 04:14 PM

nmrlearner

Senior Member

Join Date: Jan 2005

Posts: 23,732

Points: 193,617, Level: 100

Level up: 0%, 0 Points needed

Activity: 50.7%

Last Achievements

Award-Showcase

NMR Credits: 0

NMR Points: 193,617

Downloads: 0

Uploads: 0

A General Mechanism for the Propagation of MutationalEffects in Proteins

A General Mechanism for the Propagation of MutationalEffects in Proteins

Biochemistry
DOI: 10.1021/acs.biochem.6b00798

More...

Did you find this post helpful?

Similar Threads
Thread	Thread Starter	Forum	Replies	Last Post
Mechanism of the Flavoprotein l-HydroxynicotineOxidase: Kinetic Mechanism, Substrate Specificity, Reaction Product,and Roles of Active-Site Residues Mechanism of the Flavoprotein l-HydroxynicotineOxidase: Kinetic Mechanism, Substrate Specificity, Reaction Product,and Roles of Active-Site Residues http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/bichaw/0/bichaw.ahead-of-print/acs.biochem.5b01325/20160115/images/medium/bi-2015-01325p_0010.gif Biochemistry DOI: 10.1021/acs.biochem.5b01325 http://feeds.feedburner.com/~ff/acs/bichaw?d=yIl2AUoC8zA http://feeds.feedburner.com/~r/acs/bichaw/~4/dRyDnVshmpk More...	nmrlearner	Journal club	0	01-16-2016 04:41 AM
[NMR paper] NMR Methods for the Study of Instrinsically Disordered Proteins Structure, Dynamics, and Interactions: General Overview and Practical Guidelines. NMR Methods for the Study of Instrinsically Disordered Proteins Structure, Dynamics, and Interactions: General Overview and Practical Guidelines. Related Articles NMR Methods for the Study of Instrinsically Disordered Proteins Structure, Dynamics, and Interactions: General Overview and Practical Guidelines. Adv Exp Med Biol. 2015;870:49-122 Authors: Brutscher B, Felli IC, Gil-Caballero S, Hošek T, Kümmerle R, Piai A, Pierattelli R, Sólyom Z Abstract Thanks to recent improvements in NMR instrumentation, pulse sequence design, and...	nmrlearner	Journal club	0	09-21-2015 03:01 PM
Erratic proteins: New insights into a transport mechanism - YottaFire <img alt="" height="1" width="1" /> Erratic proteins: New insights into a transport mechanism YottaFire â??Only through employing modern nuclear magnetic resonance spectroscopy, it has become possible to detect this dynamic behavior within Skp.â?? Transporting the membrane protein in such a changing state does not require energy and allows for its rapid ... and more » Erratic proteins: New insights into a transport mechanism - YottaFire More...	nmrlearner	Online News	0	12-18-2013 04:00 PM
Erratic proteins: New insights into a transport mechanism - Toronto NewsFIX <img alt="" height="1" width="1" /> Erratic proteins: New insights into a transport mechanism Toronto NewsFIX â??Only through employing modern nuclear magnetic resonance spectroscopy, it has become possible to detect this dynamic behavior within Skp.â?? Transporting the membrane protein in such a changing state does not require energy and allows for its rapid ... and more » Erratic proteins: New insights into a transport mechanism - Toronto NewsFIX More...	nmrlearner	Online News	0	11-18-2013 08:39 AM
Erratic proteins: New insights into a transport mechanism - Phys.Org <img alt="" height="1" width="1" /> Erratic proteins: New insights into a transport mechanism Phys.Org "Only through employing modern nuclear magnetic resonance spectroscopy, it has become possible to detect this dynamic behavior within Skp." Transporting the membrane protein in such a changing state does not require energy and allows for its rapid ... Erratic proteins: New insights into a transport mechanism - Phys.Org More...	nmrlearner	Online News	0	09-30-2013 03:48 PM
[NMR paper] General framework for studying the dynamics of folded and nonfolded proteins by NMR r General framework for studying the dynamics of folded and nonfolded proteins by NMR relaxation spectroscopy and MD simulation. Related Articles General framework for studying the dynamics of folded and nonfolded proteins by NMR relaxation spectroscopy and MD simulation. J Am Chem Soc. 2002 Apr 24;124(16):4522-34 Authors: Prompers JJ, Brüschweiler R A general framework is presented for the interpretation of NMR relaxation data of proteins. The method, termed isotropic reorientational eigenmode dynamics (iRED), relies on a principal component...	nmrlearner	Journal club	0	11-24-2010 08:49 PM
[NMR paper] Analysis of error propagation from NMR-derived internuclear distances into molecular Analysis of error propagation from NMR-derived internuclear distances into molecular structure of cyclo-pro-gly. Related Articles Analysis of error propagation from NMR-derived internuclear distances into molecular structure of cyclo-pro-gly. J Magn Reson. 1998 Dec;135(2):454-65 Authors: Dzakula Z, Jurani? , DeRider ML, Westler WM, Macura S, Markley JL Analytical expressions have been derived that translate uncertainties in distance constraints (obtained from NMR investigations) into uncertainties in atom positions in the maximum likelihood...	nmrlearner	Journal club	0	11-17-2010 11:15 PM
[NMR paper] A general method for assigning NMR spectra of denatured proteins using 3D HC(CO)NH-TO A general method for assigning NMR spectra of denatured proteins using 3D HC(CO)NH-TOCSY triple resonance experiments. Related Articles A general method for assigning NMR spectra of denatured proteins using 3D HC(CO)NH-TOCSY triple resonance experiments. J Biomol NMR. 1993 Mar;3(2):225-31 Authors: Logan TM, Olejniczak ET, Xu RX, Fesik SW A general approach for assigning the resonances of uniformly 15N- and 13C-labeled proteins in their unfolded state is presented. The assignment approach takes advantage of the spectral dispersion of the amide...	nmrlearner	Journal club	0	08-21-2010 11:53 PM

« Previous Thread | Next Thread »

Posting Rules
You may not post new threads You may not post replies You may not post attachments You may not edit your posts BB code is On Smilies are On [IMG] code is On HTML code is On Trackbacks are Off Pingbacks are Off Refbacks are Off