Related ArticlesExploring interactions between lipids and amyloid-forming proteins: a review for applying fluorescence and NMR techniques.
Chem Phys Lipids. 2021 Feb 15;:105062
Authors: Chang Z, Deng J, Zhao W, Yang J
Abstract
A hallmark of Alzheimer's, Parkinson's, and other amyloid diseases is the assembly of amyloid proteins into amyloid aggregates or fibrils. In many cases, the formation and cytotoxicity of amyloid assemblies are associated with their interaction with cell membranes. Despite studied for many years, the characterization of the interaction is challenged for reasons on the multiple aggregation states of amyloid-forming proteins, transient and weak interactions in the complex system. As several strategies such as computation biology, spectroscopy, and imaging methods have been performed, there is an urgent need to detail the molecular mechanism in different time scales and high resolutions. This review highlighted the recent applications of fluorescence, solution and solid-state NMR in exploring the interactions between amyloid protein and membranes attributing to their advantages of high sensitivity and atomic resolution.
PMID: 33600803 [PubMed - as supplied by publisher]
[NMR paper] Biochemical and NMR characterization of the interactions of Vav2-SH2 domain with lipids and the EphA2 juxtamembrane region on membrane.
Biochemical and NMR characterization of the interactions of Vav2-SH2 domain with lipids and the EphA2 juxtamembrane region on membrane.
http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/https:--portlandpress.com-images-pubmed-logo.png Related Articles Biochemical and NMR characterization of the interactions of Vav2-SH2 domain with lipids and the EphA2 juxtamembrane region on membrane.
Biochem J. 2020 Sep 08;:
Authors: Ge L, Wu B, Zhang Y, Wang J, Zhao H, Wang J
Abstract
Vav2 is a ubiquitous guanine nucleotide...
Exploring Structural Biology: Tools & Techniques Used in the Study of Membrane Protein Structure â?? Biotechnology ... - satPRnews (press release)
Exploring Structural Biology: Tools & Techniques Used in the Study of Membrane Protein Structure â?? Biotechnology ... - satPRnews (press release)
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Exploring Structural Biology: Tools & Techniques Used in the Study of Membrane Protein Structure â?? Biotechnology ...
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Unique and innovative methods are being developed for membrane protein extraction, characterization, and structure determination of biologically significant membrane proteins, opening doors in the membrane structural biology market. Scientists are ...
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03-11-2018 04:50 AM
Exploring Structural Biology: Tools & Techniques Used in the Study of Membrane Protein Structure - MilTech
Exploring Structural Biology: Tools & Techniques Used in the Study of Membrane Protein Structure - MilTech
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Exploring Structural Biology: Tools & Techniques Used in the Study of Membrane Protein Structure
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Unique and innovative methods are being developed for membrane protein extraction, characterization, and structure determination of biologically significant membrane proteins, opening doors in the membrane structural biology market. Scientists are ...
and more »
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01-09-2018 09:41 AM
Solid state NMR of salivary calculi: Proline-rich salivary proteins, citrate, polysaccharides, lipids, and organic–mineral interactions
Solid state NMR of salivary calculi: Proline-rich salivary proteins, citrate, polysaccharides, lipids, and organic–mineral interactions
Publication date: Available online 3 January 2016
Source:Comptes Rendus Chimie</br>
Author(s): Yang Li, David G. Reid, Dominique Bazin, Michel Daudon, Melinda J. Duer</br>
Solid state NMR (ssNMR) can characterize mineral (31P) and organic (13C) components of human salivary stones (n*=*8). All show apatitic 31P spectra. 13C ssNMR indicates more protein, of more consistent composition, than apatitic uroliths, with prominent...
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01-04-2016 07:49 PM
[NMR paper] Interactions of Polyphenols with Plasma Proteins: Insights from Analytical Techniques.
Interactions of Polyphenols with Plasma Proteins: Insights from Analytical Techniques.
Related Articles Interactions of Polyphenols with Plasma Proteins: Insights from Analytical Techniques.
Curr Drug Metab. 2013 Jan 17;
Authors: Jaldappagari S, Balakrishnan S, Hegde AH, Teradal NL, Narayan PS
Abstract
Phenolic compounds are commonly found in natural sources like plant-based foods and beverages.* These compounds have received much attention due to their unique biological properties. Polyphenols possess a significant binding affinity...
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02-03-2013 10:19 AM
Interactions of gemini surfactants with two model proteins: NMR, CD, and fluorescence spectroscopies
Interactions of gemini surfactants with two model proteins: NMR, CD, and fluorescence spectroscopies
1 March 2012
Publication year: 2012
Source:Journal of Colloid and Interface Science, Volume 369, Issue 1</br>
</br>
Gemini surfactants have two polar head groups and two hydrocarbon tails. Compared with conventional surfactants, geminis have much lower (?M vs. mM) critical micelle concentrations and possess slower (ms vs. ?s) monomer ? micelle kinetics. The structure of the gemini surfactants studied is ·2Br- where s =4, 5, or 6. Our objective is to reveal the effect...
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Exploring NMR ensembles of calcium binding proteins: perspectives to design inhibitors of protein-protein interactions.
Exploring NMR ensembles of calcium binding proteins: perspectives to design inhibitors of protein-protein interactions.
Exploring NMR ensembles of calcium binding proteins: perspectives to design inhibitors of protein-protein interactions.
BMC Struct Biol. 2011 May 12;11(1):24
Authors: Isvoran A, Badel A, Craescu CT, Miron S, Miteva MA
ABSTRACT: BACKGROUND: Disrupting protein-protein interactions by small organic molecules is nowadays a promising strategy employed to block protein targets involved in different pathologies. However, structural...
Exploring interactions between lipids and amyloid-forming proteins: a review for applying fluorescence and NMR techniques.
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