Related ArticlesEnhanced protein fold recognition using secondary structure information from NMR.
Protein Sci. 1999 May;8(5):1127-33
Authors: Ayers DJ, Gooley PR, Widmer-Cooper A, Torda AE
NMR offers the possibility of accurate secondary structure for proteins that would be too large for structure determination. In the absence of an X-ray crystal structure, this information should be useful as an adjunct to protein fold recognition methods based on low resolution force fields. The value of this information has been tested by adding varying amounts of artificial secondary structure data and threading a sequence through a library of candidate folds. Using a literature test set, the threading method alone has only a one-third chance of producing a correct answer among the top ten guesses. With realistic secondary structure information, one can expect a 60-80% chance of finding a homologous structure. The method has then been applied to examples with published estimates of secondary structure. This implementation is completely independent of sequence homology, and sequences are optimally aligned to candidate structures with gaps and insertions allowed. Unlike work using predicted secondary structure, we test the effect of differing amounts of relatively reliable data.
[NMR paper] NMR assignments, secondary structure, and global fold of calerythrin, an EF-hand calc
NMR assignments, secondary structure, and global fold of calerythrin, an EF-hand calcium-binding protein from Saccharopolyspora erythraea.
Related Articles NMR assignments, secondary structure, and global fold of calerythrin, an EF-hand calcium-binding protein from Saccharopolyspora erythraea.
Protein Sci. 1999 Dec;8(12):2580-8
Authors: Aitio H, Annila A, Heikkinen S, Thulin E, Drakenberg T, Kilpeläinen I
Calerythrin is a 20 kDa calcium-binding protein isolated from gram-positive bacterium Saccharopolyspora erythraea. Based on amino acid...
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[NMR paper] Using neural network predicted secondary structure information in automatic protein N
Using neural network predicted secondary structure information in automatic protein NMR assignment.
Related Articles Using neural network predicted secondary structure information in automatic protein NMR assignment.
J Chem Inf Comput Sci. 1997 Nov-Dec;37(6):1086-94
Authors: Choy WY, Sanctuary BC, Zhu G
In CAPRI, an automated NMR assignment software package that was developed in our laboratory, both chemical shift values and coupling topologies of spin patterns are used in a procedure for amino acids recognition. By using a knowledge base of...
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[NMR paper] 1H-NMR-derived secondary structure and overall fold of a natural anatoxin from the sc
1H-NMR-derived secondary structure and overall fold of a natural anatoxin from the scorpion Androctonus australis hector.
http://www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--www3.interscience.wiley.com-aboutus-images-wiley_interscience_pubmed_logo_FREE_120x27.gif Related Articles 1H-NMR-derived secondary structure and overall fold of a natural anatoxin from the scorpion Androctonus australis hector.
Eur J Biochem. 1997 Aug 1;247(3):1118-26
Authors: Blanc E, Hassani O, Meunier S, Mansuelle P, Sampieri F, Rochat H, Darbon H
The venom of the...
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[NMR paper] 1H-NMR-derived secondary structure and the overall fold of the potent anti-mammal and
1H-NMR-derived secondary structure and the overall fold of the potent anti-mammal and anti-insect toxin III from the scorpion Leiurus quinquestriatus quinquestriatus.
http://www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--www3.interscience.wiley.com-aboutus-images-wiley_interscience_pubmed_logo_FREE_120x27.gif Related Articles 1H-NMR-derived secondary structure and the overall fold of the potent anti-mammal and anti-insect toxin III from the scorpion Leiurus quinquestriatus quinquestriatus.
Eur J Biochem. 1996 Mar 1;236(2):395-404
Authors: Landon C,...
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[NMR paper] Use of graph theory for secondary structure recognition and sequential assignment in
Use of graph theory for secondary structure recognition and sequential assignment in heteronuclear (13C, 15N) NMR spectra: application to HU protein from Bacillus stearothermophilus.
Related Articles Use of graph theory for secondary structure recognition and sequential assignment in heteronuclear (13C, 15N) NMR spectra: application to HU protein from Bacillus stearothermophilus.
Biopolymers. 1996 Nov;39(5):691-707
Authors: van Geerestein-Ujah EC, Mariani M, Vis H, Boelens R, Kaptein R
A computer-assisted procedure, based upon a branch of...
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[NMR paper] Assignments, secondary structure, global fold, and dynamics of chemotaxis Y protein u
Assignments, secondary structure, global fold, and dynamics of chemotaxis Y protein using three- and four-dimensional heteronuclear (13C,15N) NMR spectroscopy.
Related Articles Assignments, secondary structure, global fold, and dynamics of chemotaxis Y protein using three- and four-dimensional heteronuclear (13C,15N) NMR spectroscopy.
Biochemistry. 1994 Sep 6;33(35):10731-42
Authors: Moy FJ, Lowry DF, Matsumura P, Dahlquist FW, Krywko JE, Domaille PJ
NMR spectroscopy has been used to study recombinant Escherichia coli CheY, a 128-residue...
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[NMR paper] 1H-NMR resonance assignments, secondary structure, and global fold of the TR1C fragme
1H-NMR resonance assignments, secondary structure, and global fold of the TR1C fragment of turkey skeletal troponin C in the calcium-free state.
Related Articles 1H-NMR resonance assignments, secondary structure, and global fold of the TR1C fragment of turkey skeletal troponin C in the calcium-free state.
Biochemistry. 1993 Apr 6;32(13):3461-7
Authors: Findlay WA, Sykes BD
The TR1C fragment of turkey skeletal muscle TnC (residues 12-87) comprises the two regulatory calcium binding sites of the protein. Complete assignments of the 1H-NMR...