When Heterotrimeric G Proteins Are Not Activated by G Protein-Coupled Receptors: Structural Insights and Evolutionary Conservation
When Heterotrimeric G Proteins Are Not Activated by G Protein-Coupled Receptors: Structural Insights and Evolutionary Conservation
http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/bichaw/0/bichaw.ahead-of-print/acs.biochem.7b00845/20171016/images/medium/bi-2017-00845a_0003.gif
Biochemistry
DOI: 10.1021/acs.biochem.7b00845
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10-17-2017 10:19 AM
[NMR paper] The application of DOSY NMR and molecular dynamics simulations to explore the mechanism(s) of micelle binding of antimicrobial peptides containing unnatural amino acids.
The application of DOSY NMR and molecular dynamics simulations to explore the mechanism(s) of micelle binding of antimicrobial peptides containing unnatural amino acids.
http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--media.wiley.com-assets-7315-19-Wiley_FullText_120x30_orange.png Related Articles The application of DOSY NMR and molecular dynamics simulations to explore the mechanism(s) of micelle binding of antimicrobial peptides containing unnatural amino acids.
Biopolymers. 2013 Aug;99(8):548-61
Authors: Clark TD,...
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04-23-2016 09:24 PM
Measurementof State-Specific Association Constantsin Allosteric Sensors through Molecular Stapling and NMR
Measurementof State-Specific Association Constantsin Allosteric Sensors through Molecular Stapling and NMR
Kody J. Moleschi, Madoka Akimoto and Giuseppe Melacini
http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/jacsat/0/jacsat.ahead-of-print/jacs.5b06557/20150817-01/images/medium/ja-2015-06557b_0007.gif
Journal of the American Chemical Society
DOI: 10.1021/jacs.5b06557
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nmrlearner
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08-17-2015 07:21 PM
[NMR paper] Measurement of State-Specific Association Constants in Allosteric Sensors through Molecular Stapling and NMR.
Measurement of State-Specific Association Constants in Allosteric Sensors through Molecular Stapling and NMR.
Related Articles Measurement of State-Specific Association Constants in Allosteric Sensors through Molecular Stapling and NMR.
J Am Chem Soc. 2015 Aug 6;
Authors: Moleschi KJ, Akimoto M, Melacini G
Abstract
Allostery is a ubiquitous mechanism to control biological function and arises from the coupling of inhibitory and binding equilibria. The extent of coupling reflects the inactive vs. active state selectivity of the...
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08-08-2015 12:17 PM
[NMR paper] NMR Analysis of Tuning Cross-Strand Phe/Tyr/Trp - Trp Interactions in Designed ?-Hairpin Peptides: Terminal Switch from L- to D-Amino Acid as a Strategy for ?-Hairpin Capping.
NMR Analysis of Tuning Cross-Strand Phe/Tyr/Trp - Trp Interactions in Designed ?-Hairpin Peptides: Terminal Switch from L- to D-Amino Acid as a Strategy for ?-Hairpin Capping.
Related Articles NMR Analysis of Tuning Cross-Strand Phe/Tyr/Trp - Trp Interactions in Designed ?-Hairpin Peptides: Terminal Switch from L- to D-Amino Acid as a Strategy for ?-Hairpin Capping.
J Phys Chem B. 2015 Apr 7;
Authors: Makwana KM, Mahalakshmi R
Abstract
Interaction among the side chains of aromatic amino acids is a well-known mechanism of protein...
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04-09-2015 03:47 AM
Paramagnetic relaxation enhancement of membrane proteins by incorporation of the metal-chelating unnatural amino acid 2-amino-3-(8-hydroxyquinolin-3-yl)propanoic acid (HQA)
Paramagnetic relaxation enhancement of membrane proteins by incorporation of the metal-chelating unnatural amino acid 2-amino-3-(8-hydroxyquinolin-3-yl)propanoic acid (HQA)
Abstract
The use of paramagnetic constraints in protein NMR is an active area of research because of the benefits of long-range distance measurements (>10Â*Ã?). One of the main issues in successful execution is the incorporation of a paramagnetic metal ion into diamagnetic proteins. The most common metal ion tags are relatively long aliphatic chains attached to the side chain of a...
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11-28-2014 11:37 AM
15N-permethylated amino acids as efficient probes for MRI-DNP applications
From The DNP-NMR Blog:
15N-permethylated amino acids as efficient probes for MRI-DNP applications
Chiavazza, E., et al., 15N-permethylated amino acids as efficient probes for MRI-DNP applications. Contrast Media Mol Imaging, 2013. 8(5): p. 417-21.
http://www.ncbi.nlm.nih.gov/pubmed/23740812
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02-21-2014 08:51 PM
An efficient protocol for incorporation of an unnatural amino acid in perdeuterated recombinant proteins using glucose-based media
An efficient protocol for incorporation of an unnatural amino acid in perdeuterated recombinant proteins using glucose-based media
Abstract The in vivo incorporation of unnatural amino acids into proteins is a well-established technique requiring an orthogonal tRNA/aminoacyl-tRNA synthetase pair specific for the unnatural amino acid that is incorporated at a position encoded by a TAG amber codon. Although this technology provides unique opportunities to engineer protein structures, poor protein yields are usually obtained in deuterated media, hampering its application in the protein NMR...
Efficient Amino-Sulfhydryl Stapling on Peptides and Proteins Using Bifunctional NHS-Activated Acrylamides
Linear Mode
