Parkinson's Protein Aggregates Seen in Action Destroying Neurons in Brain - Parkinson's News Today
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Parkinson's Protein Aggregates Seen in Action Destroying Neurons in Brain
Parkinson's News Today
To overcome this issue, researchers used advanced techniques, including a method called solid state nuclear magnetic resonance spectroscopy, to stabilize the oligomers long enough to study their structure and actions. Looking at both toxic and non ...
Parkinson's Protein Aggregates Seen in Action...
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12-20-2017 08:47 AM
[NMR paper] Determination of glucose exchange rates and permeability of erythrocyte membrane in preeclampsia and subsequent oxidative stress-related protein damage using dynamic-(19)F-NMR.
Determination of glucose exchange rates and permeability of erythrocyte membrane in preeclampsia and subsequent oxidative stress-related protein damage using dynamic-(19)F-NMR.
Related Articles Determination of glucose exchange rates and permeability of erythrocyte membrane in preeclampsia and subsequent oxidative stress-related protein damage using dynamic-(19)F-NMR.
J Biomol NMR. 2017 Feb 21;:
Authors: Dickinson E, Arnold JR, Fisher J
Abstract
The cause of the pregnancy condition preeclampsia (PE) is thought to be endothelial...
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02-23-2017 11:08 AM
Determination of glucose exchange rates and permeability of erythrocyte membrane in preeclampsia and subsequent oxidative stress-related protein damage using dynamic- 19 F-NMR
Determination of glucose exchange rates and permeability of erythrocyte membrane in preeclampsia and subsequent oxidative stress-related protein damage using dynamic- 19 F-NMR
Abstract
The cause of the pregnancy condition preeclampsia (PE) is thought to be endothelial dysfunction caused by oxidative stress. As abnormal glucose tolerance has also been associated with PE, we use a fluorinated-mimic of this metabolite to establish whether any oxidative damage to lipids and proteins in the erythrocyte membrane has increased cell membrane permeability....
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02-22-2017 06:28 PM
Researchers 'Watch' Protein Aggregation Process That Leads to Parkinson's Disease - Parkinson's News Today
Researchers 'Watch' Protein Aggregation Process That Leads to Parkinson's Disease - Parkinson's News Today
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Parkinson's News Today
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Researchers 'Watch' Protein Aggregation Process That Leads to Parkinson's Disease
Parkinson's News Today
In the meantime, researchers could follow this â??unfoldingâ?? of the proteins using a technique called nuclear magnetic resonance (NMR) spectroscopy. NMR gave the team access to the folding...
nmrlearner
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12-02-2016 07:45 AM
Molecules Discovered for Neurodegenerative Diseases - Drug Discovery & Development
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Drug Discovery & Development
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Molecules Discovered for Neurodegenerative Diseases
Drug Discovery & Development
Researchers used an array of techniques, including X-ray fiber diffraction and nuclear magnetic resonance spectroscopy, to demonstrate the activities of GAIM. They discovered that GAIM effectively binds to multiple types of misfolded proteins during ...
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Molecules Discovered for...
nmrlearner
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04-23-2014 05:13 AM
[NMR paper] NMR reveals double occupancy of quinone-type ligands in the catalytic quinone binding site of the Na+-translocating NADH:Quinone oxidoreductase from Vibrio cholerae.
NMR reveals double occupancy of quinone-type ligands in the catalytic quinone binding site of the Na+-translocating NADH:Quinone oxidoreductase from Vibrio cholerae.
http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--highwire.stanford.edu-icons-externalservices-pubmed-standard-jbc_final.gif Related Articles NMR reveals double occupancy of quinone-type ligands in the catalytic quinone binding site of the Na+-translocating NADH:Quinone oxidoreductase from Vibrio cholerae.
J Biol Chem. 2013 Oct 18;288(42):30597-606
Authors: Nedielkov R,...
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01-01-2014 03:05 PM
[NMR paper] 1H NMR Based Targeted Metabolite Profiling for Understanding the Complex Relationship Connecting Oxidative Stress with Endometriosis.
1H NMR Based Targeted Metabolite Profiling for Understanding the Complex Relationship Connecting Oxidative Stress with Endometriosis.
1H NMR Based Targeted Metabolite Profiling for Understanding the Complex Relationship Connecting Oxidative Stress with Endometriosis.
Biomed Res Int. 2013;2013:329058
Authors: Jana SK, Dutta M, Joshi M, Srivastava S, Chakravarty B, Chaudhury K
Abstract
Accumulating evidence indicates the active role of oxidative stress in the development of endometriosis; however, the mechanism of reactive oxygen species...
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08-29-2013 01:53 PM
[NMR paper] NMR-based metabolomics of urine in a mouse model of Alzheimer's disease: identification of oxidative stress biomarkers.
NMR-based metabolomics of urine in a mouse model of Alzheimer's disease: identification of oxidative stress biomarkers.
Related Articles NMR-based metabolomics of urine in a mouse model of Alzheimer's disease: identification of oxidative stress biomarkers.
J Clin Biochem Nutr. 2013 Mar;52(2):133-8
Authors: Fukuhara K, Ohno A, Ota Y, Senoo Y, Maekawa K, Okuda H, Kurihara M, Okuno A, Niida S, Saito Y, Takikawa O
Abstract
Alzheimer's disease (AD) is the most common cause of neurodegenerative dementia among elderly patients. A biomarker...