Disuse muscle atrophy (DMA) is a significant healthcare challenge characterized by progressive loss of muscle mass and function resulting from prolonged inactivity. The development of effective strategies for muscle recovery is essential. In this study, we established a DMA mouse model through hindlimb suspension to evaluate the therapeutic potential of lactate in alleviating the detrimental effects on the gastrocnemius muscle. Using NMR-based metabolomic analysis, we investigated the metabolic...
[NMR paper] Application of Benchtop NMR for Metabolomics Study Using Feces of Mice with DSS-Induced Colitis
Application of Benchtop NMR for Metabolomics Study Using Feces of Mice with DSS-Induced Colitis
Nuclear magnetic resonance (NMR)-based metabolomics, which comprehensively measures metabolites in biological systems and investigates their response to various perturbations, is widely used in research to identify biomarkers and investigate the pathogenesis of underlying diseases. However, further applications of high-field superconducting NMR for medical purposes and field research are restricted by its high cost and low accessibility. In this study, we applied a low-field, benchtop NMR...
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05-27-2023 01:56 AM
[NMR paper] NMR-based metabolomic analysis for the effects of moxibustion on imiquimod-induced psoriatic mice
NMR-based metabolomic analysis for the effects of moxibustion on imiquimod-induced psoriatic mice
CONCLUSIONS: This study reveals the molecular mechanisms underlying the effects of moxibustion treatment on the skin lesions of psoriasis, potentially improving the clinical efficacy of moxibustion.
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09-03-2022 03:47 AM
[NMR paper] Metabolic fate of glucose in the brain of APP/PS1 transgenic mice at 10*months of age: a 13C NMR metabolomic study.
Metabolic fate of glucose in the brain of APP/PS1 transgenic mice at 10*months of age: a 13C NMR metabolomic study.
http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--production.springer.de-OnlineResources-Logos-springerlink.gif Related Articles Metabolic fate of glucose in the brain of APP/PS1 transgenic mice at 10*months of age: a 13C NMR metabolomic study.
Metab Brain Dis. 2018 10;33(5):1661-1668
Authors: Zhou Q, Zheng H, Chen J, Li C, Du Y, Xia H, Gao H
Abstract
Alzheimer's disease (AD) has been...
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05-09-2019 05:55 AM
[NMR paper] Plasma metabolomics study of the hepatoprotective effect of glycyrrhetinic acid on realgar-induced sub-chronic hepatotoxicity in mice via 1H NMR analysis.
Plasma metabolomics study of the hepatoprotective effect of glycyrrhetinic acid on realgar-induced sub-chronic hepatotoxicity in mice via 1H NMR analysis.
http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--linkinghub.elsevier.com-ihub-images-PubMedLink.gif Related Articles Plasma metabolomics study of the hepatoprotective effect of glycyrrhetinic acid on realgar-induced sub-chronic hepatotoxicity in mice via 1H NMR analysis.
J Ethnopharmacol. 2017 Aug 17;208:36-43
Authors: Huo T, Fang Y, Zhang Y, Wang Y, Feng C, Yuan M, Wang S,...
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02-08-2018 04:32 PM
[NMR paper] ¹H-NMR and MS based metabolomics study of the intervention effect of curcumin on hyperlipidemia mice induced by high-fat diet.
¹H-NMR and MS based metabolomics study of the intervention effect of curcumin on hyperlipidemia mice induced by high-fat diet.
http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--www.plosone.org-images-pone_120x30.png http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--www.ncbi.nlm.nih.gov-corehtml-pmc-pmcgifs-pubmed-pmc.gif Related Articles ¹H-NMR and MS based metabolomics study of the intervention effect of curcumin on hyperlipidemia mice induced by high-fat diet.
PLoS One. 2015;10(3):e0120950
Authors: Li...
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02-06-2016 03:10 PM
[NMR paper] Hippocampal neurochemical changes in senescent mice induced with chronic injection of D-galactose and NaNO?: an in vitro high-resolution NMR spectroscopy study at 9.4T.
Hippocampal neurochemical changes in senescent mice induced with chronic injection of D-galactose and NaNO?: an in vitro high-resolution NMR spectroscopy study at 9.4T.
http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--www.plosone.org-images-pone_120x30.png http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--www.pubmedcentral.nih.gov-corehtml-pmc-pmcgifs-pubmed-pmc.gif Related Articles Hippocampal neurochemical changes in senescent mice induced with chronic injection of D-galactose and NaNO?: an in vitro high-resolution NMR spectroscopy...
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01-13-2015 02:31 PM
[NMR paper] Prediction of response of collagen-induced arthritis rats to methotrexate: an (1)H-NMR-based urine metabolomic analysis.
Prediction of response of collagen-induced arthritis rats to methotrexate: an (1)H-NMR-based urine metabolomic analysis.
http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--production.springer.de-OnlineResources-Logos-springerlink.gif Related Articles Prediction of response of collagen-induced arthritis rats to methotrexate: an (1)H-NMR-based urine metabolomic analysis.
J Huazhong Univ Sci Technolog Med Sci. 2012 Jun;32(3):438-43
Authors: Chen Z, Tu S, Hu Y, Wang Y, Xia Y, Jiang Y
Abstract
Over one half the...
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09-12-2014 06:37 PM
(1)H-NMR-based metabolomic study on resistance to diet-induced obesity in AHNAK knock
(1)H-NMR-based metabolomic study on resistance to diet-induced obesity in AHNAK knock-out mice.
(1)H-NMR-based metabolomic study on resistance to diet-induced obesity in AHNAK knock-out mice.
Biochem Biophys Res Commun. 2010 Nov 18;
Authors: Kim IY, Jung J, Jang M, Ahn YG, Shin JH, Choi JW, Sohn MR, Shin SM, Kang DG, Lee HS, Bae YS, Ryu DH, Seong JK, Hwang GS
AHNAK is a giant protein of approximately 700 kD identified in human neuroblastomas and skin epithelial cells. Recently, we found that AHNAK knock-out (AHNAK(-/-)) mice have a strong...
Deciphering the Therapeutic Role of Lactate in Combating Disuse-Induced Muscle Atrophy: An NMR-Based Metabolomic Study in Mice
Linear Mode
