In the original publication, Figures 3 and 6 wereÂ*displayed incorrectlyÂ*due to a mistake made by the publisher. The correct version of Figs. 3 and 6 are given below.
A suite of 19 F based relaxation dispersion experiments to assess biomolecular motions
A suite of 19 F based relaxation dispersion experiments to assess biomolecular motions
Abstract
Proteins and nucleic acids are highly dynamic bio-molecules that can populate a variety of conformational states. NMR relaxation dispersion (RD) methods are uniquely suited to quantify the associated kinetic and thermodynamic parameters. Here, we present a consistent suite of 19F-based CPMG, on-resonance R1Ď? and off-resonance R1Ď? RD experiments. We validate these experiments by studying the unfolding transition of a 7.5Â*kDa cold...
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10-01-2020 11:37 AM
[NMR paper] Resolving biomolecular motion and interactions by R2 and R1? Relaxation Dispersion NMR.
Resolving biomolecular motion and interactions by R2 and R1? Relaxation Dispersion NMR.
Related Articles Resolving biomolecular motion and interactions by R2 and R1? Relaxation Dispersion NMR.
Methods. 2018 Apr 25;:
Authors: Walinda E, Morimoto D, Sugase K
Abstract
Among the tools of structural biology, NMR spectroscopy is unique in that it not only derives a static three-dimensional structure, but also provides an atomic-level description of the local fluctuations and global dynamics around this static structure. A battery of...
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05-01-2018 10:20 AM
[NMR paper] Acquiring and processing ultrafast biomolecular 2D NMR experiments using a referenced-based correction.
Acquiring and processing ultrafast biomolecular 2D NMR experiments using a referenced-based correction.
Acquiring and processing ultrafast biomolecular 2D NMR experiments using a referenced-based correction.
J Biomol NMR. 2016 Sep 28;
Authors: Seginer A, Olsen GL, Frydman L
Abstract
Thanks to their special spatiotemporal encoding/decoding scheme, ultrafast (UF) NMR sequences can deliver arbitrary 2D spectra following a single excitation. Regardless of their nature, these sequences have in common their tracing of a path in the -...
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09-30-2016 10:11 AM
Acquiring and processing ultrafast biomolecular 2D NMR experiments using a referenced-based correction
Acquiring and processing ultrafast biomolecular 2D NMR experiments using a referenced-based correction
Abstract
Thanks to their special spatiotemporal encoding/decoding scheme, ultrafast (UF) NMR sequences can deliver arbitrary 2D spectra following a single excitation. Regardless of their nature, these sequences have in common their tracing of a path in the \({\hbox {F}_{1}}\) â?? \(t_{2}\) ...
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09-29-2016 06:58 AM
[NMR paper] Motions and Entropies in Proteins as Seen in NMR Relaxation Experiments and Molecular Dynamics Simulations.
Motions and Entropies in Proteins as Seen in NMR Relaxation Experiments and Molecular Dynamics Simulations.
Related Articles Motions and Entropies in Proteins as Seen in NMR Relaxation Experiments and Molecular Dynamics Simulations.
J Phys Chem B. 2014 Oct 28;
Authors: Allnér O, Foloppe N, Nilsson L
Abstract
Molecular dynamics simulations of E. coli glutaredoxin1 in water have been performed to relate the dynamical parameters and entropy obtained in NMR relaxation experiments, with results extracted from simulated trajectory...
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10-29-2014 03:51 PM
Correction for Li et al., Mechanism of E-cadherin dimerization probed by NMR relaxation dispersion [Correction]
Correction for Li et al., Mechanism of E-cadherin dimerization probed by NMR relaxation dispersion
...
Date: 2013-11-26
BIOPHYSICS AND COMPUTATIONAL BIOLOGY Correction for “Mechanism of E-cadherin dimerization probed by NMR relaxation dispersion,” by Ying Li, Nicole L. Altorelli, Fabiana Bahna, Barry Honig, Lawrence Shapiro, and Arthur G. Palmer III, which appeared in issue 41, October 8, 2013, of Proc Natl Acad Sci USA (110:16462–16467; first published September... Read More
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Number: 48
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11-27-2013 01:50 AM
Can Enzyme Engineering Benefit from the Modulation of Protein Motions? Lessons Learned from NMR Relaxation Dispersion Experiments.
Can Enzyme Engineering Benefit from the Modulation of Protein Motions? Lessons Learned from NMR Relaxation Dispersion Experiments.
Can Enzyme Engineering Benefit from the Modulation of Protein Motions? Lessons Learned from NMR Relaxation Dispersion Experiments.
Protein Pept Lett. 2011 Jan 11;
Authors:
Despite impressive progress in protein engineering and design, our ability to create new and efficient enzyme activities remains a laborious and time-consuming endeavor. In the past few years, intricate combinations of rational mutagenesis, directed...
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01-13-2011 12:00 PM
Suite of Six NMR Relaxation Dispersion Experiments to Study Multiple-Site Exchange in Proteins
http://pubs.acs.org/isubscribe/journals/jacsat/127/i44/figures/ja054550en00001.gif
Multiple-Site Exchange in Proteins Studied with a Suite of Six NMR Relaxation Dispersion Experiments: An Application to the Folding of a Fyn SH3 Domain Mutant
Dmitry M. Korzhnev, Philipp Neudecker, Anthony Mittermaier, Vladislav Yu. Orekhov, and Lewis E. Kay*
Contribution from the Departments of Medical Genetics, Biochemistry, and Chemistry, The University of Toronto, Toronto, Ontario M5S 1A8, Canada, and Swedish NMR Center at Göteborg University, Box 465, 405 30 Göteborg, Sweden
J. Am. Chem....
Correction to: A suite of 19 F based relaxation dispersion experiments to assess biomolecular motions
Linear Mode
