CONCLUSIONS: In this large-scale postprandial metabolomic study, circulating metabolites were highly variable between individuals following sequential mixed meals. Findings suggest that a meal challenge may yield postprandial responses divergent from fasting measures, specifically for glycolysis, essential amino acid, ketone body and lipoprotein size metabolites.
[NMR paper] Correlations between the NMR Lipoprotein Profile, APOE Genotype, and Cholesterol Efflux Capacity of Fasting Plasma from Cognitively Healthy Elderly Adults
Correlations between the NMR Lipoprotein Profile, APOE Genotype, and Cholesterol Efflux Capacity of Fasting Plasma from Cognitively Healthy Elderly Adults
Cholesterol efflux capacity (CEC) is of interest given its potential relationship with several important clinical conditions including Alzheimer's disease. The inactivation of the APOE locus in mouse models supports the idea that it is involved in determining the CEC. With that in mind, we examine the impact of the plasma metabolome profile and the APOE genotype on the CEC in cognitively healthy elderly subjects. The study subjects were...
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[NMR paper] New insights into the influence of Monofluorination on Dimyristoylphosphatidylcholine membrane properties: A solid-state NMR study.
New insights into the influence of Monofluorination on Dimyristoylphosphatidylcholine membrane properties: A solid-state NMR study.
New insights into the influence of Monofluorination on Dimyristoylphosphatidylcholine membrane properties: A solid-state NMR study.
Biochim Biophys Acta. 2017 Dec 06;:
Authors: Gagnon MC, Strandberg E, Ulrich AS, Paquin JF, Auger M
Abstract
Solid-state 19F NMR spectroscopy is a method of choice to study the interactions between lipid membranes and other molecules such as peptides, proteins or drugs....
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12-11-2017 12:45 PM
[NMR paper] Structural and Dynamic Insights of the Interaction between Tritrpticin and Micelles: An NMR Study.
Structural and Dynamic Insights of the Interaction between Tritrpticin and Micelles: An NMR Study.
http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--linkinghub.elsevier.com-ihub-images-cellhub.gif Related Articles Structural and Dynamic Insights of the Interaction between Tritrpticin and Micelles: An NMR Study.
Biophys J. 2016 Dec 20;111(12):2676-2688
Authors: Santos TL, Moraes A, Nakaie CR, Almeida FC, Schreier S, Valente AP
Abstract
A large number of antimicrobial peptides (AMPs) acts with high selectivity...
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Study reveals insights into protein linked to cancer and Alzheimer's disease - Phys.Org
http://www.bionmr.com//t2.gstatic.com/images?q=tbn:ANd9GcSWI4MEyAKap5sPkmjZDVOz54ftSxtRd9JGH5zRAazKibUp4bqE85WneiO-T0Zw4Yodm98XzkWk
Phys.Org
<img alt="" height="1" width="1">
Study reveals insights into protein linked to cancer and Alzheimer's disease
Phys.Org
Using high-field nuclear magnetic resonance (NMR) spectroscopy, Peng and his group propose answers to both questions. He explained with a metaphor. "When Pin 1 is by itself, its two domains, call them 'A' and 'B,' have greater physical contact," he said.
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Study reveals insights into protein linked to cancer...
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06-07-2016 12:27 AM
Study reveals insights into protein linked to cancer and Alzheimer's disease - ND Newswire
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ND Newswire
<img alt="" height="1" width="1">
Study reveals insights into protein linked to cancer and Alzheimer's disease
ND Newswire
Using high-field nuclear magnetic resonance (NMR) spectroscopy, Peng and his group propose answers to both questions. He explained with a metaphor. â??When Pin 1 is by itself, its two domains, call them 'A' and 'B,' have greater physical contact,â?? he said.
and more »
Study reveals insights into protein linked to...
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06-03-2016 04:52 PM
[NMR paper] NMR study of short ?(1-3)-glucans provides insights into the structure and interaction with Dectin-1.
NMR study of short ?(1-3)-glucans provides insights into the structure and interaction with Dectin-1.
Related Articles NMR study of short ?(1-3)-glucans provides insights into the structure and interaction with Dectin-1.
Glycoconj J. 2013 Nov 29;
Authors: Hanashima S, Ikeda A, Tanaka H, Adachi Y, Ohno N, Takahashi T, Yamaguchi Y
Abstract
?(1-3)-Glucans, abundant in fungi, have the potential to activate the innate immune response against various pathogens. Although part of the action is exerted through the C-type lectin-like receptor...
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12-03-2013 12:49 PM
(1)H NMR study of monocrotaline and its metabolites in human blood.
(1)H NMR study of monocrotaline and its metabolites in human blood.
(1)H NMR study of monocrotaline and its metabolites in human blood.
Food Chem Toxicol. 2011 Aug 6;
Authors: Yang YC, Crowder J, Wardle NJ, Yang L, White KN, Wang ZT, Annie Bligh SW
Monocrotaline (MCT) is a naturally occurring hepatotoxic pyrrolizidine alkaloid found in plants. This investigation is aimed at furthering the understanding of the role of blood in mediating the transport of MCT and its reactive metabolites in humans. Reactions of monocrotaline and its metabolites,...
Characterisation of Fasting and Postprandial NMR Metabolites: Insights from the ZOE PREDICT 1 Study
Linear Mode
