Preparation of protein samples for NMR structure, function, and small-molecule screening studies.
Preparation of protein samples for NMR structure, function, and small-molecule screening studies.
Preparation of protein samples for NMR structure, function, and small-molecule screening studies.
Methods Enzymol. 2011;493:21-60
Authors: Acton TB, Xiao R, Anderson S, Aramini J, Buchwald WA, Ciccosanti C, Conover K, Everett J, Hamilton K, Huang YJ, Janjua H, Kornhaber G, Lau J, Lee DY, Liu G, Maglaqui M, Ma L, Mao L, Patel D, Rossi P, Sahdev S, Shastry R, Swapna GV, Tang Y, Tong S, Wang D, Wang H, Zhao L, Montelione GT
In this chapter, we...
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03-05-2011 01:02 PM
[NMR paper] Solution structure and dynamics of integral membrane proteins by NMR: a case study in
Solution structure and dynamics of integral membrane proteins by NMR: a case study involving the enzyme PagP.
Related Articles Solution structure and dynamics of integral membrane proteins by NMR: a case study involving the enzyme PagP.
Methods Enzymol. 2005;394:335-50
Authors: Hwang PM, Kay LE
Solution NMR spectroscopy is rapidly becoming an important technique for the study of membrane protein structure and dynamics. NMR experiments on large perdeuterated proteins typically exploit the favorable relaxation properties of backbone amide...
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11-24-2010 11:14 PM
[NMR paper] Transient protein interactions studied by NMR spectroscopy: the case of cytochrome C
Transient protein interactions studied by NMR spectroscopy: the case of cytochrome C and adrenodoxin.
Related Articles Transient protein interactions studied by NMR spectroscopy: the case of cytochrome C and adrenodoxin.
Biochemistry. 2003 Jun 17;42(23):7068-76
Authors: Worrall JA, Reinle W, Bernhardt R, Ubbink M
The interaction between yeast iso-1-cytochrome c (C102T) and two forms of bovine adrenodoxin, the wild type and a truncated form comprising residues 4-108, has been investigated using a combination of one- and two-dimensional...
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11-24-2010 09:01 PM
[NMR paper] NMR structure determination of a novel conotoxin, [Pro 7,13] alpha A-conotoxin PIVA.
NMR structure determination of a novel conotoxin, alpha A-conotoxin PIVA.
http://www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--pubs.acs.org-images-acspubs.jpg Related Articles NMR structure determination of a novel conotoxin, alpha A-conotoxin PIVA.
Biochemistry. 1997 Feb 18;36(7):1669-77
Authors: Han KH, Hwang KJ, Kim SM, Kim SK, Gray WR, Olivera BM, Rivier J, Shon KJ
A high-resolution solution conformation of a novel conotoxin, alpha A-conotoxin PIVA, GCCGSYPNAACHPCSCKDROSYCGQ-NH2, has been determined by two-dimensional 1H NMR methods...
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08-22-2010 03:31 PM
[NMR paper] NMR structure determination of a novel conotoxin, [Pro 7,13] alpha A-conotoxin PIVA.
NMR structure determination of a novel conotoxin, alpha A-conotoxin PIVA.
http://www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--pubs.acs.org-images-acspubs.jpg Related Articles NMR structure determination of a novel conotoxin, alpha A-conotoxin PIVA.
Biochemistry. 1997 Feb 18;36(7):1669-77
Authors: Han KH, Hwang KJ, Kim SM, Kim SK, Gray WR, Olivera BM, Rivier J, Shon KJ
A high-resolution solution conformation of a novel conotoxin, alpha A-conotoxin PIVA, GCCGSYPNAACHPCSCKDROSYCGQ-NH2, has been determined by two-dimensional 1H NMR methods...
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08-22-2010 03:03 PM
[NMR paper] A case history. NMR studies of the structure of a small protein, omega-conotoxin MVII
A case history. NMR studies of the structure of a small protein, omega-conotoxin MVIIA.
Related Articles A case history. NMR studies of the structure of a small protein, omega-conotoxin MVIIA.
Methods Mol Biol. 1997;60:337-62
Authors: MacLachlan LK, Middleton DA, Edwards AJ, Reid DG
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08-22-2010 03:03 PM
[Ryan's blog] A Case for more NMR, and maybe even Automated Structure Verification?
Source: Ryan's blog
A Case for more NMR, and maybe even Automated Structure Verification?
I've spent a lot of time over the past couple of years visiting both scientists and directors in Pharma and having discussions around the concept of automated structure verification, whether or not there is enough characterization being done on screens,...
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08-21-2010 08:57 PM
[Ryan's blog] From FID to Structure in 30 Minutes? Investigating the CASE Limiting Step
Source: Ryan's blog
From FID to Structure in 30 Minutes? Investigating the CASE Limiting Step
In yesterday's post I pointed you to an article that has become the most accessed article of all time in the Journal of Cheminformatics, co-authored by representatives of ACD/Labs. This article is a very comprehensive outline of the different approaches,...
A case history. NMR studies of the structure of a small protein, omega-conotoxin MVII
Linear Mode
