[NMR paper] (19)F NMR viewed through two different lenses: ligand-observed and protein-observed (19)F NMR applications for fragment-based drug discovery
(19)F NMR viewed through two different lenses: ligand-observed and protein-observed (19)F NMR applications for fragment-based drug discovery
^(19)F NMR has emerged as a powerful tool in drug discovery, particularly in fragment-based screens. The favorable magnetic resonance properties of the fluorine-19 nucleus, the general absence of fluorine in biological settings, and its ready incorporation into both small molecules and biopolymers, has enabled multiple applications of ^(19)F NMR using labeled small molecules and proteins in biophysical, biochemical, and cellular experiments. This...
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10-27-2021 10:50 PM
Sample Ripening through Nanophase Separation Impacts the Performance of Dynamic Nuclear Polarization
From The DNP-NMR Blog:
Sample Ripening through Nanophase Separation Impacts the Performance of Dynamic Nuclear Polarization
Weber, E., et al., Sample Ripening through Nanophase Separation Impacts the Performance of Dynamic Nuclear Polarization. Angew. Chem., 2018: p. n/a-n/a.
http://dx.doi.org/10.1002/ange.201800493
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03-21-2018 04:04 PM
[NMR paper] Fast and Efficient Fragment-Based Lead Generation by Fully Automated Processing and Analysis of Ligand-Observed NMR Binding Data.
Fast and Efficient Fragment-Based Lead Generation by Fully Automated Processing and Analysis of Ligand-Observed NMR Binding Data.
http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--pubs.acs.org-images-pubmed-acspubs.jpg Related Articles Fast and Efficient Fragment-Based Lead Generation by Fully Automated Processing and Analysis of Ligand-Observed NMR Binding Data.
J Med Chem. 2016 Apr 14;59(7):3303-10
Authors: Peng C, Frommlet A, Perez M, Cobas C, Blechschmidt A, Dominguez S, Lingel A
Abstract
NMR...
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09-28-2016 06:22 PM
[NMR paper] Protein-Observed Fluorine NMR is a Complementary Ligand Discovery Method to 1H CPMG Ligand-Observed NMR.
Protein-Observed Fluorine NMR is a Complementary Ligand Discovery Method to 1H CPMG Ligand-Observed NMR.
http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--pubs.acs.org-images-pubmed-acspubs.jpg Related Articles Protein-Observed Fluorine NMR is a Complementary Ligand Discovery Method to 1H CPMG Ligand-Observed NMR.
ACS Chem Biol. 2016 Sep 14;
Authors: Urick AK, Calle Jiménez LP, Espinosa JF, Hu H, Pomerantz WC
Abstract
To evaluate its potential as a ligand discovery tool, we compare a newly developed...
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09-22-2016 06:31 AM
[Question from NMRWiki Q&A forum] Best way to make a 2D figure
Best way to make a 2D figure
Hi all,
I need to make a figure containing a 2D NMR spectrum for a paper. Has anyone figured out a good way to do this? The journal requires the figure to be editable, thus I need to end up with PostScript, eps, or similar (not jpg, png, etc).
Thanks,Mark
How much does a NMR technician usually make?
http://www.chem.unl.edu/nmr/400mhz.htmlwell our professor said it was around 8 k a month, but im just seeing if those figures are correctim guessin no one has any of these at their school?
Blending to Make Nonhealable Polymers Healable: Nanophase Separation Observed by CP/MAS 13C NMR Analysis
Linear Mode
