Related ArticlesBiophysical investigations on L1210 mouse leukemia cells treated with activated cyclophosphamide metabolites: determination of selective properties of DNA-interstrand and DNA-protein cross-linking mechanisms (alkaline elution and 31P-NMR-spectroscopy) and some aspects of the combination drug and radiotherapy.
Strahlenther Onkol. 1990 Feb;166(2):157-63
Authors: Ulmer W
Dose-effect relationships have been studied by using L1210 mouse leukemia cells treated with the activated cyclophosphamide derivatives 4-hydroperoxy-cyclophosphamide and 4-sulfido-cyclophosphamide. The combined treatment of the cells with the drugs and irradiation with X-rays indicates synergistic effects, if the irradiation of the cells is performed four to six hours after the drug treatment. DNA-interstrand and DNA-protein cross-linkings have been determined by an alkaline elution procedure. The yield of cross-linkings has been monitoring by either the 3H-14C method or by a 31P-NMR Fourier spectroscopy analysis of the eluted substrates.
[NMR paper] NMR backbone assignment of the mitogen-activated protein (MAP) kinase p38.
NMR backbone assignment of the mitogen-activated protein (MAP) kinase p38.
Related Articles NMR backbone assignment of the mitogen-activated protein (MAP) kinase p38.
J Biomol NMR. 2005 Jun;32(2):175
Authors: Vogtherr M, Saxena K, Grimme S, Betz M, Schieborr U, Pescatore B, Langer T, Schwalbe H
nmrlearner
Journal club
0
11-25-2010 08:21 PM
[NMR paper] NMR structure of activated CheY.
NMR structure of activated CheY.
Related Articles NMR structure of activated CheY.
J Mol Biol. 2000 Mar 31;297(3):543-51
Authors: Cho HS, Lee SY, Yan D, Pan X, Parkinson JS, Kustu S, Wemmer DE, Pelton JG
The CheY protein is the response regulator in bacterial chemotaxis. Phosphorylation of a conserved aspartyl residue induces structural changes that convert the protein from an inactive to an active state. The short half-life of the aspartyl-phosphate has precluded detailed structural analysis of the active protein. Persistent activation of...
nmrlearner
Journal club
0
11-18-2010 09:15 PM
Biophysical Society 55th Annual Meeting
Biophysical Society 55th Annual Meeting
The 2011 Annual Meeting will be held in the Baltimore Convention Center, Baltimore, Maryland, March 5-9, 2011.
Sunday, October 3, 2010, is the abstract submission deadline and deadline to apply for travel awards and the SRAA competition.
Abstract Submission
http://www.biophysics.org/2011meeting/tabid/2086/Default.aspx
Student, International, Minority, and CPOW Travel Award Applications http://www.biophysics.org/2011meeting/tabid/2171/Default.aspx
nmrlearner
Conferences
0
09-23-2010 07:04 AM
[NMR paper] 31P-NMR of liver peroxisome membranes from normal and clofibrate-treated rats.
31P-NMR of liver peroxisome membranes from normal and clofibrate-treated rats.
Related Articles 31P-NMR of liver peroxisome membranes from normal and clofibrate-treated rats.
Cell Mol Biol (Noisy-le-grand). 1993 Jul;39(5):479-89
Authors: Serafini B, Cimini A, Sette M, Sartori C
Normal and clofibrate-induced rat liver peroxisomes were studied in order to correlate the drug-elicited modifications of membrane permeability and fluidity with changes of the phospholipid component. The phospholipid composition and membrane fluidity of purified...
nmrlearner
Journal club
0
08-21-2010 11:53 PM
[NMR paper] Activation of the phosphosignaling protein CheY. II. Analysis of activated mutants by
Activation of the phosphosignaling protein CheY. II. Analysis of activated mutants by 19F NMR and protein engineering.
http://www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--www.pubmedcentral.nih.gov-corehtml-pmc-pmcgifs-pubmed-pmc-MS.gif Related Articles Activation of the phosphosignaling protein CheY. II. Analysis of activated mutants by 19F NMR and protein engineering.
J Biol Chem. 1993 Jun 25;268(18):13089-96
Authors: Bourret RB, Drake SK, Chervitz SA, Simon MI, Falke JJ
The Escherichia coli CheY protein is activated by phosphorylation,...
nmrlearner
Journal club
0
08-21-2010 11:53 PM
[NMR paper] Biophysical aspects of the integrated combination of cytostatic drugs with radiothera
Biophysical aspects of the integrated combination of cytostatic drugs with radiotherapy. Part 1: In vitro investigations on the kinetics of activated isophosphamide metabolites and the determination of selective properties of DNA-interstrand and DNA-protein crosslinking mechanisms using 31P-NMR spectroscopy.
Related Articles Biophysical aspects of the integrated combination of cytostatic drugs with radiotherapy. Part 1: In vitro investigations on the kinetics of activated isophosphamide metabolites and the determination of selective properties of DNA-interstrand and DNA-protein...
nmrlearner
Journal club
0
08-21-2010 11:16 PM
[NMR paper] 1H and 31P NMR and HPLC studies of mouse L1210 leukemia cell extracts: the effect of
1H and 31P NMR and HPLC studies of mouse L1210 leukemia cell extracts: the effect of Au(I) and Cu(I) diphosphine complexes on the cell metabolism.
Related Articles 1H and 31P NMR and HPLC studies of mouse L1210 leukemia cell extracts: the effect of Au(I) and Cu(I) diphosphine complexes on the cell metabolism.
Magn Reson Med. 1991 Mar;18(1):142-58
Authors: Berners-Price SJ, Sant ME, Christopherson RI, Kuchel PW
The effect of the antitumor complex Cl (where dppe is Ph2P(CH2)2PPh2) on the overall metabolism of cultured mouse L1210 leukemia cells...