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Old 03-18-2021, 05:17 PM
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Default Assignments of (19)F NMR resonances and exploration of dynamics in a long-chain flavodoxin

Assignments of (19)F NMR resonances and exploration of dynamics in a long-chain flavodoxin

Flavodoxin is a small protein that employs a non-covalently bound flavin to mediate single-electron transfer at low potentials. The long-chain flavodoxins possess a long surface loop that is proposed to interact with partner proteins. We have incorporated ^(19)F-labeled tyrosine in long-chain flavodoxin from Rhodopseudomonas palustris to gain a probe of possible loop dynamics, exploiting the presence of a Tyr in the long loop in addition to Tyr residues near the flavin. We report ^(19)F...

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