Nuclear magnetic resonance (NMR)-based metabolomics, which comprehensively measures metabolites in biological systems and investigates their response to various perturbations, is widely used in research to identify biomarkers and investigate the pathogenesis of underlying diseases. However, further applications of high-field superconducting NMR for medical purposes and field research are restricted by its high cost and low accessibility. In this study, we applied a low-field, benchtop NMR...
[NMR paper] NMR-based metabolomic analysis for the effects of moxibustion on imiquimod-induced psoriatic mice
NMR-based metabolomic analysis for the effects of moxibustion on imiquimod-induced psoriatic mice
CONCLUSIONS: This study reveals the molecular mechanisms underlying the effects of moxibustion treatment on the skin lesions of psoriasis, potentially improving the clinical efficacy of moxibustion.
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09-03-2022 03:47 AM
[NMR paper] The Protective Effect of Basic Fibroblast Growth Factor in Intestine of db/db Mice: A (1)H NMR-Based Metabolomics Investigation
The Protective Effect of Basic Fibroblast Growth Factor in Intestine of db/db Mice: A (1)H NMR-Based Metabolomics Investigation
Diabetic enteropathy (DE) is a diabetic complication and affects the quality of life for which there are limited therapies. In this study, db/db mice were administered with a basic fibroblast growth factor (bFGF) to explore its therapeutic effect on the intestine. ¹H NMR-based metabolomics was applied to investigate the metabolic pattern. H&E and PAS staining were used to observe the morphological phenotypes related to intestinal barrier function. Tight junction...
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10-27-2021 10:49 AM
Monitoring of hydrogenation by benchtop NMR with parahydrogen-induced polarization
From The DNP-NMR Blog:
Monitoring of hydrogenation by benchtop NMR with parahydrogen-induced polarization
Jeong, Keunhong, Sein Min, Heelim Chae, and Sung Keon Namgoong. “Monitoring of Hydrogenation by Benchtop NMR with Parahydrogen-Induced Polarization.” Magnetic Resonance in Chemistry, August 29, 2018.
https://doi.org/10.1002/mrc.4791.
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11-25-2018 06:02 AM
[NMR paper] Plasma metabolomics study of the hepatoprotective effect of glycyrrhetinic acid on realgar-induced sub-chronic hepatotoxicity in mice via 1H NMR analysis.
Plasma metabolomics study of the hepatoprotective effect of glycyrrhetinic acid on realgar-induced sub-chronic hepatotoxicity in mice via 1H NMR analysis.
http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--linkinghub.elsevier.com-ihub-images-PubMedLink.gif Related Articles Plasma metabolomics study of the hepatoprotective effect of glycyrrhetinic acid on realgar-induced sub-chronic hepatotoxicity in mice via 1H NMR analysis.
J Ethnopharmacol. 2017 Aug 17;208:36-43
Authors: Huo T, Fang Y, Zhang Y, Wang Y, Feng C, Yuan M, Wang S,...
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02-08-2018 04:32 PM
[NMR paper] ¹H-NMR and MS based metabolomics study of the intervention effect of curcumin on hyperlipidemia mice induced by high-fat diet.
¹H-NMR and MS based metabolomics study of the intervention effect of curcumin on hyperlipidemia mice induced by high-fat diet.
http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--www.plosone.org-images-pone_120x30.png http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--www.ncbi.nlm.nih.gov-corehtml-pmc-pmcgifs-pubmed-pmc.gif Related Articles ¹H-NMR and MS based metabolomics study of the intervention effect of curcumin on hyperlipidemia mice induced by high-fat diet.
PLoS One. 2015;10(3):e0120950
Authors: Li...
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02-06-2016 03:10 PM
[NMR paper] Hippocampal neurochemical changes in senescent mice induced with chronic injection of D-galactose and NaNO?: an in vitro high-resolution NMR spectroscopy study at 9.4T.
Hippocampal neurochemical changes in senescent mice induced with chronic injection of D-galactose and NaNO?: an in vitro high-resolution NMR spectroscopy study at 9.4T.
http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--www.plosone.org-images-pone_120x30.png http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--www.pubmedcentral.nih.gov-corehtml-pmc-pmcgifs-pubmed-pmc.gif Related Articles Hippocampal neurochemical changes in senescent mice induced with chronic injection of D-galactose and NaNO?: an in vitro high-resolution NMR spectroscopy...
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01-13-2015 02:31 PM
[NMR paper] Fecal and urinary NMR-based metabolomics unveil an aging signature in mice.
Fecal and urinary NMR-based metabolomics unveil an aging signature in mice.
Related Articles Fecal and urinary NMR-based metabolomics unveil an aging signature in mice.
Exp Gerontol. 2013 Oct 29;
Authors: Calvani R, Brasili E, Praticò G, Capuani G, Tomassini A, Marini F, Sciubba F, Finamore A, Roselli M, Marzetti E, Miccheli A
Abstract
BACKGROUND: Aging is characterized by derangements in multiple metabolic pathways that progressively constrict the homeostatic reserve (homeostenosis). The signature of metabolic alterations that accompany...
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11-05-2013 06:53 PM
[NMR paper] Behavioral, neurochemical and morphological changes induced by the overexpression of munc18-1a in brain of mice: relevance to schizophrenia.
Behavioral, neurochemical and morphological changes induced by the overexpression of munc18-1a in brain of mice: relevance to schizophrenia.
http://www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--www.nature.com-images-lo_tp.gif Related Articles Behavioral, neurochemical and morphological changes induced by the overexpression of munc18-1a in brain of mice: relevance to schizophrenia.
Transl Psychiatry. 2013;3:e221
Authors: Urigüen L, Gil-Pisa I, Munarriz-Cuezva E, Berrocoso E, Pascau J, Soto-Montenegro ML, Gutiérrez-Adán A, Pintado B, Madrigal JL, Castro E,...
Application of Benchtop NMR for Metabolomics Study Using Feces of Mice with DSS-Induced Colitis
Linear Mode
