Canine lymphoma represents a biologically and metabolically heterogeneous group of neoplasms that arise from malignant transformation of lymphoid cells. An accurate diagnosis is crucial because of its impact on survival. Current diagnostic methods include clinical laboratory tests and imaging, most of which are invasive and lack sensitivity and specificity. Interestingly, recent work in cancer patients focuses on the search for biomarkers for diagnosis, investigation of treatment response...
[NMR paper] Serum Lipoprotein Profiling by NMR Spectroscopy Reveals Alterations in HDL-1 and HDL-2 Apo-A2 Subfractions in Alzheimer's Disease
Serum Lipoprotein Profiling by NMR Spectroscopy Reveals Alterations in HDL-1 and HDL-2 Apo-A2 Subfractions in Alzheimer's Disease
Identifying biomarkers for Alzheimer's disease (AD) is crucial, due to its complex pathology, which involves dysfunction in lipid transport, contributing to neuroinflammation, synaptic loss, and impaired amyloid-? clearance. Nuclear magnetic resonance (NMR) is able to quantify and stratify lipoproteins. The study investigated lipoproteins in blood from AD patients, aiming to evaluate their diagnostic potential. Serum and plasma were collected from AD patients (n...
nmrlearner
Journal club
0
11-13-2024 07:00 PM
[NMR paper] Sex differences in the 1H NMR metabolic profile of serum in cardiovascular risk patients.
Sex differences in the 1H NMR metabolic profile of serum in cardiovascular risk patients.
http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--www.nature.com-images-lo_npg.gif http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/https:--www.ncbi.nlm.nih.gov-corehtml-pmc-pmcgifs-pubmed-pmc.png Related Articles Sex differences in the 1H NMR metabolic profile of serum in cardiovascular risk patients.
Sci Rep. 2019 02 20;9(1):2380
Authors: Barba I, Andrés M, Picón I, Aguade-Bruix S, Garcia-Dorado D
Abstract
...
nmrlearner
Journal club
0
09-17-2020 07:46 AM
[NMR paper] Cell Metabolic Profiling of Colorectal Cancer via 1H NMR.
Cell Metabolic Profiling of Colorectal Cancer via 1H NMR.
Related Articles Cell Metabolic Profiling of Colorectal Cancer via 1H NMR.
Clin Chim Acta. 2020 Jul 21;:
Authors: Ge S, Zhang Q, Tian Y, Hao L, Duan J, Zhang B
Abstract
BACKGROUND: Protein arginine methyltransferase 5 (PRMT5) belongs to a large family of protein arginine methyltransferases (PRMTs) that play essential role in gene transcription and regulate tumorigenesis. However, the role of PRMT5 in the regulation of cancer cell metabolism remains unclear.
nmrlearner
Journal club
0
07-27-2020 09:21 PM
Cellular signals: NMR metabolic profiling
Cellular signals: NMR metabolic profiling
http://www.spectroscopynow.com/common/images/thumbnails/15bf6b54ee3.jpgA novel NMR technique developed by researchers at the University of Toronto Scarborough, Canada, can for the first time obtain undistorted high-resolution profiles of the molecules and metabolites present within a living organism.
Read the rest at Spectroscopynow.com
nmrlearner
General
0
05-15-2017 02:25 AM
[NMR paper] Metabolic profiling in kidneys of Atlantic salmon infected with Aeromonas salmonicida based on (1)H NMR.
Metabolic profiling in kidneys of Atlantic salmon infected with Aeromonas salmonicida based on (1)H NMR.
Related Articles Metabolic profiling in kidneys of Atlantic salmon infected with Aeromonas salmonicida based on (1)H NMR.
Fish Shellfish Immunol. 2016 Aug 27;
Authors: Liu PF, Du Y, Meng L, Li X, Liu Y
Abstract
Aeromonas salmonicida, an important pathogenic bacterium which induces furunculosis, is globally causing increased risks in Atlantic salmon (Salmo salar) farming. Although the kidney is the main target organ of A....
nmrlearner
Journal club
0
09-01-2016 07:21 PM
[NMR paper] Malignancy-associated metabolic profiling of human glioma cell lines using 1H NMR spectroscopy.
Malignancy-associated metabolic profiling of human glioma cell lines using 1H NMR spectroscopy.
Related Articles Malignancy-associated metabolic profiling of human glioma cell lines using 1H NMR spectroscopy.
Mol Cancer. 2014 Aug 27;13(1):197
Authors: Shao W, Gu J, Huang C, Liu D, Huang H, Huang Z, Lin Z, Yang W, Liu K, Lin D, Ji T
Abstract
BACKGROUND: Ambiguity in malignant transformation of glioma has made prognostic diagnosis very challenging. Tumor malignant transformation is closely correlated with specific alterations...
nmrlearner
Journal club
0
08-29-2014 05:36 PM
Colon cancer calculated: Metabolic profiling
Colon cancer calculated: Metabolic profiling
http://www.spectroscopynow.com/common/images/thumbnails/14077d20717.jpgNuclear magnetic resonance (NMR) spectroscopy can be used to obtain a metabolic fingerprint of cancer of the bowel and so determine how far advanced the disease is, according to UK researchers.
Read the rest at Spectroscopynow.com
nmrlearner
General
0
08-15-2013 07:22 AM
Metabolic profiling of vitamin C deficiency in Guloâ??/â?? mice using proton NMR spectroscopy
Metabolic profiling of vitamin C deficiency in Guloâ??/â?? mice using proton NMR spectroscopy
Abstract Nutrient deficiencies are an ongoing problem in many populations and ascorbic acid is a key vitamin whose mild or acute absence leads to a number of conditions including the famously debilitating scurvy. As such, the biochemical effects of ascorbate deficiency merit ongoing scrutiny, and the Gulo knockout mouse provides a useful model for the metabolomic examination of vitamin C deficiency. Like humans, these animals are incapable of synthesizing ascorbic acid but with dietary...
Application of (1)H NMR Metabolic Profiling of Serum in Canine Multicentric Lymphoma
Linear Mode
