Allosteric code of NMR chemical shifts [Biophysics and Computational Biology]
 

Allosteric code of NMR chemical shifts [Biophysics and Computational Biology]

VanSchouwen, B., Melacini, G....
Date: 2016-08-23

One of the broadest definitions of allostery is in terms of long-range couplings between remote sites within a molecular system (1–4). Allosteric couplings are critical to understand the molecular basis of physiological regulatory mechanisms as well as of pathological deregulation (1–4). Allostery is also opening new opportunities in drug design... Read More


PNAS:
Number: 34
Volume: 113