Probing allosteric interactions in homo-oligomeric molecular machines using solution NMR spectroscopy [Biophysics and Computational Biology]
Probing allosteric interactions in homo-oligomeric molecular machines using solution NMR spectroscopy
Yuki Toyama, Lewis E. Kay...
Date: 2021-12-10
Developments in solution NMR spectroscopy have significantly impacted the biological questions that can now be addressed by this methodology. By means of illustration, we present here a perspective focusing on studies of a number of molecular machines that are critical for cellular homeostasis. The role of NMR in elucidating the... Read More
PNAS:
Number: 50
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[NMR paper] Probing allosteric interactions in homo-oligomeric molecular machines using solution NMR spectroscopy
Probing allosteric interactions in homo-oligomeric molecular machines using solution NMR spectroscopy
Developments in solution NMR spectroscopy have significantly impacted the biological questions that can now be addressed by this methodology. By means of illustration, we present here a perspective focusing on studies of a number of molecular machines that are critical for cellular homeostasis. The role of NMR in elucidating the structural dynamics of these important molecules is emphasized, focusing specifically on intersubunit allosteric communication in homo-oligomers. In many...
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[ASAP] De Novo-Designed ?-Sheet Heme Proteins
De Novo-Designed ?-Sheet Heme Proteins
https://pubs.acs.org/na101/home/literatum/publisher/achs/journals/content/bichaw/0/bichaw.ahead-of-print/acs.biochem.0c00662/20210203/images/medium/bi0c00662_0009.gif
Biochemistry
DOI: 10.1021/acs.biochem.0c00662
http://feeds.feedburner.com/~r/acs/bichaw/~4/58aty_0vNFo
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Visualizing Specific Cross-Protomer Interactions in the Homo-Oligomeric Membrane Protein Proteorhodopsin by Dynamic-Nuclear-Polarization-Enhanced Solid-State NMR
Visualizing Specific Cross-Protomer Interactions in the Homo-Oligomeric Membrane Protein Proteorhodopsin by Dynamic-Nuclear-Polarization-Enhanced Solid-State NMR
Jakob Maciejko, Michaela Mehler, Jagdeep Kaur, Tobias Lieblein, Nina Morgner, Olivier Ouari, Paul Tordo, Johanna Becker-Baldus and Clemens Glaubitz
http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/jacsat/0/jacsat.ahead-of-print/jacs.5b03606/20150713/images/medium/ja-2015-03606j_0008.gif
Journal of the American Chemical Society
DOI: 10.1021/jacs.5b03606
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[NMR paper] Visualizing specific Cross-Protomer Interactions in the Homo-Oligomeric Membrane Protein Proteorhodopsin by DNP-enhanced Solid-state NMR.
Visualizing specific Cross-Protomer Interactions in the Homo-Oligomeric Membrane Protein Proteorhodopsin by DNP-enhanced Solid-state NMR.
Visualizing specific Cross-Protomer Interactions in the Homo-Oligomeric Membrane Protein Proteorhodopsin by DNP-enhanced Solid-state NMR.
J Am Chem Soc. 2015 Jun 23;
Authors: Maciejko J, Mehler M, Kaur J, Lieblein T, Morgner N, Ouari O, Tordo P, Becker-Baldus J, Glaubitz C
Abstract
Membrane proteins often form oligomeric complexes within the lipid bilayer but factors controlling their assembly...
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06-24-2015 01:08 PM
[NMR paper] Systematic solution to homo-oligomeric structures determined by NMR.
Systematic solution to homo-oligomeric structures determined by NMR.
http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--media.wiley.com-assets-2250-98-WileyOnlineLibrary-Button_120x27px_FullText.gif Related Articles Systematic solution to homo-oligomeric structures determined by NMR.
Proteins. 2015 Jan 23;
Authors: Martin JW, Zhou P, Donald BR
Abstract
Protein structure determination by NMR has predominantly relied on simulated annealing-based conformational search for a converged fold using primarily...