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NMR processing:
MDD
NMR assignment:
Backbone:
Autoassign
MARS
UNIO Match
PINE
Side-chains:
UNIO ATNOS-Ascan
NOEs:
UNIO ATNOS-Candid
UNIO Candid
ASDP
Structure from NMR restraints:
Ab initio:
GeNMR
Cyana
XPLOR-NIH
ASDP
UNIO ATNOS-Candid
UNIO Candid
Fragment-based:
BMRB CS-Rosetta
Rosetta-NMR (Robetta)
Template-based:
GeNMR
I-TASSER
Refinement:
Amber
Structure from chemical shifts:
Fragment-based:
WeNMR CS-Rosetta
BMRB CS-Rosetta
Homology-based:
CS23D
Simshift
Torsion angles from chemical shifts:
Preditor
TALOS
Promega- Proline
Secondary structure from chemical shifts:
CSI (via RCI server)
TALOS
MICS caps, β-turns
d2D
PECAN
Flexibility from chemical shifts:
RCI
Interactions from chemical shifts:
HADDOCK
Chemical shifts re-referencing:
Shiftcor
UNIO Shiftinspector
LACS
CheckShift
RefDB
NMR model quality:
NOEs, other restraints:
PROSESS
PSVS
RPF scores
iCing
Chemical shifts:
PROSESS
CheShift2
Vasco
iCing
RDCs:
DC
Anisofit
Pseudocontact shifts:
Anisofit
Protein geomtery:
Resolution-by-Proxy
PROSESS
What-If
iCing
PSVS
MolProbity
SAVES2 or SAVES4
Vadar
Prosa
ProQ
MetaMQAPII
PSQS
Eval123D
STAN
Ramachandran Plot
Rampage
ERRAT
Verify_3D
Harmony
Quality Control Check
NMR spectrum prediction:
FANDAS
MestReS
V-NMR
Flexibility from structure:
Backbone S2
Methyl S2
B-factor
Molecular dynamics:
Gromacs
Amber
Antechamber
Chemical shifts prediction:
From structure:
Shiftx2
Sparta+
Camshift
CH3shift- Methyl
ArShift- Aromatic
ShiftS
Proshift
PPM
CheShift-2- Cα
From sequence:
Shifty
Camcoil
Poulsen_rc_CS
Disordered proteins:
MAXOCC
Format conversion & validation:
CCPN
From NMR-STAR 3.1
Validate NMR-STAR 3.1
NMR sample preparation:
Protein disorder:
DisMeta
Protein solubility:
camLILA
ccSOL
Camfold
camGroEL
Zyggregator
Isotope labeling:
UPLABEL
Solid-state NMR:
sedNMR


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Old 09-06-2005, 08:08 AM
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I found the following position on NANUC website:


Description:
This position supports ongoing collaborative research between Dr. Valerie Booth at Memorial University and NewLab Clinical Research Inc. Our studies are aimed atelucidating structural information about membrane-associated proteins that are potentialdrug targets. The postdoctoral researcher will use both solution and solid state NMR, combined with computer modeling, to determine structures of molecules of interest. Thesemolecules include peptide ligands in their G-protein coupled receptor bound conformation, aswell as other membrane-associated proteins that have been identified as potential targets of therapeutic molecules to treat psoriasis and other diseases. Materials for the NMR studies,including G-protein coupled receptors in sufficient quantities for experimental studies andcustom isotope labeled peptide ligand, have been provided by collaborators.

Application Procedure:
Please email your CV, a short description of your research interests,and the names of three references to Dr. Valerie Booth (vbooth@mun.ca).

Salary:
Commensurate with experience

Qualifications:

PhD in a relevant field
4 or more years experience in solid and/or solution biomolecular NMR
good computer skills, especially in protein modeling
strong interest in bridging the gap between academic and private research to support development of new therapeutics

Additional Information:
The position will be physically located in the Department ofBiochemistry, Memorial University of Newfoundland. Meetings with NewLab collaboratorswill take place regularly at their nearby offices. Dr. Booth’s research group (www.physics.mun.ca/~valerie) is rapidly expanding and currently consists of one full timeresearch assistant (wet lab), one part time research assistant (computer lab), two graduatestudents and two undergraduate students. Experiments will be performed on a local 500 MHz solution NMR spectrometer, and our new 600 MHz spectrometer which will have solids(oriented and MAS) and solution capabilities. When required, experiments may also beperformed on higher field instruments in Halifax and Edmonton.

The city of St. John’s offers an exceptionally high quality of life - especially to thoseinterested in outdoor activities or the traditional music scene (www.newfoundland.com).



source: nanuc.ca/features/job_detail.php?id=3
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