postdoctoral position King's College

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postdoctoral position King's College

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NMR processing:

MDD

NMR assignment:

Backbone:

Side-chains:

NOEs:

Structure from NMR restraints:

Ab initio:

Fragment-based:

Rosetta-NMR (Robetta)

Template-based:

GeNMR

I-TASSER

Refinement:

Amber

Structure from chemical shifts:

Fragment-based:

Homology-based:

Torsion angles from chemical shifts:

Preditor

TALOS

Promega- Proline

Secondary structure from chemical shifts:

CSI (via RCI server)

TALOS

MICS caps, β-turns

d2D

PECAN

Flexibility from chemical shifts:

RCI

Interactions from chemical shifts:

HADDOCK

Chemical shifts re-referencing:

NMR model quality:

NOEs, other restraints:

Chemical shifts:

RDCs:

Pseudocontact shifts:

Protein geomtery:

SAVES2 or SAVES4

Quality Control Check

NMR spectrum prediction:

FANDAS

MestReS

V-NMR

Flexibility from structure:

Backbone S2

Methyl S2

B-factor

Molecular dynamics:

Gromacs

Amber

Antechamber

Chemical shifts prediction:

From structure:

Shiftx2

Sparta+

Camshift

CH3shift- Methyl

ArShift- Aromatic

ShiftS

Proshift

PPM

CheShift-2- Cα

From sequence:

Shifty

Camcoil

Poulsen_rc_CS

Disordered proteins:

MAXOCC

Format conversion & validation:

CCPN

From NMR-STAR 3.1

Validate NMR-STAR 3.1

NMR sample preparation:

Protein disorder:

DisMeta

Protein solubility:

Isotope labeling:

Solid-state NMR:

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03-14-2011, 05:44 PM

nmrlearner

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postdoctoral position King's College

postdoctoral position King's College

A postdoctoral position supported by the King's College London British Heart Foundation Centre of Excellence is available at King's College London in the field of ROS biology. The project is a collaborative effort amongst the groups of Prof Ajay Shah MD (Cardiovascular Division, King's College London), Dr Conte and Dr Steiner (Randall Division of Cell and Molecular Biophysics, King's College London) aimed at elucidating the molecular mechanism of controlled ROS production in higher organisms.

The project is highly interdisciplinary and will combine structural biology (X-ray and NMR) with biophysical (ITC), biochemical and cell biology work. The post requires experience in molecular biology/protein biochemistry. Proven prior experience in protein expression using the baculovirus system is also considered very important. Additional experience with biophysical methods complementary to structural biology and/or oxygen biochemistry is welcomed.

The post is available immediately and funding is initially for 18 months. Salary will be commensurate to prior experience and qualifications. Interested applicants should contact Dr Maria R Conte (sasi.conte@kcl.ac.uk) directly by submitting their CV together with the names of three referees. Informal inquiries are welcome.

Deadline for this application is 21st March 2011.

---------------------------------------------------------------------
Maria R Conte
Reader in Structural Biology
Randall Division of Cell and Molecular Biophysics
King’s College London
New Hunt’s House
Guy’s Campus
London SE1 1UL, United Kingdom

Tel +44 (0)20 7848 6194
Fax +44 (0)20 7848 6435
Email sasi.conte@kcl.ac.uk
sasi.conte@hotmail.com[IMG]https...s.blogspot.com[/IMG]

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