PhD studentship

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PhD studentship

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NMR processing:

MDD

NMR assignment:

Backbone:

Side-chains:

NOEs:

Structure from NMR restraints:

Ab initio:

Fragment-based:

Rosetta-NMR (Robetta)

Template-based:

GeNMR

I-TASSER

Refinement:

Amber

Structure from chemical shifts:

Fragment-based:

Homology-based:

Torsion angles from chemical shifts:

Preditor

TALOS

Promega- Proline

Secondary structure from chemical shifts:

CSI (via RCI server)

TALOS

MICS caps, β-turns

d2D

PECAN

Flexibility from chemical shifts:

RCI

Interactions from chemical shifts:

HADDOCK

Chemical shifts re-referencing:

NMR model quality:

NOEs, other restraints:

Chemical shifts:

RDCs:

Pseudocontact shifts:

Protein geomtery:

SAVES2 or SAVES4

Quality Control Check

NMR spectrum prediction:

FANDAS

MestReS

V-NMR

Flexibility from structure:

Backbone S2

Methyl S2

B-factor

Molecular dynamics:

Gromacs

Amber

Antechamber

Chemical shifts prediction:

From structure:

Shiftx2

Sparta+

Camshift

CH3shift- Methyl

ArShift- Aromatic

ShiftS

Proshift

PPM

CheShift-2- Cα

From sequence:

Shifty

Camcoil

Poulsen_rc_CS

Disordered proteins:

MAXOCC

Format conversion & validation:

CCPN

From NMR-STAR 3.1

Validate NMR-STAR 3.1

NMR sample preparation:

Protein disorder:

DisMeta

Protein solubility:

Isotope labeling:

Solid-state NMR:

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01-11-2012, 04:10 PM

nmrlearner

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PhD studentship

PhD studentship

A 4 year PhD studentship contract is available in my group starting september 2012 to work on the structural and functional aspects of the recognition of chromatin structure by the ING4 tumor suppressor.

We seek a motivated student with a strong interest in structural biology, and with a Master degree (to be completed before september 2012).

The PhD researcher will be involved in sample preparation and structural analysis by NMR and other techniques. The laboratory hosts two Bruker spectrometers (800 and 600 MHz) with a full complement of probes for biomolecular studies). Electron microscopy and crystallography platforms are also available at CIC bioGUNE. Functional assays will be carried out in collaboration with an external group.

CIC bioGUNE (http://www.cicbiogune.es) is a research institute in biosciences created and supported by the Basque Government in 2005 to foster bioresearch and biotech industry in the Basque Country. It is located near Bilbao, an area with a high standard of living, a mild climate and a vibrant cultural environment.

Information about the current activity and publications of the lab can be found in the following link

http://www.cicbiogune.es/secciones/i...=5&subgrupo=28

Interested applicants should send their CVs to fblanco@cicbiogune.es before the 31st of january 2012.

Best regards

---
Francisco J. Blanco
Ikerbasque Research Professor
Structural Biology Unit, CIC bioGUNE
Parque Tecnológico de Bizkaia, Edificio 800
48160 Derio, Spain
Phone: 34 946572521
Fax: 34 946572502
fblanco@cicbiogune.es
www.cicbiogune.es

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