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NMR processing:
MDD
NMR assignment:
Backbone:
Autoassign
MARS
UNIO Match
PINE
Side-chains:
UNIO ATNOS-Ascan
NOEs:
UNIO ATNOS-Candid
UNIO Candid
ASDP
Structure from NMR restraints:
Ab initio:
GeNMR
Cyana
XPLOR-NIH
ASDP
UNIO ATNOS-Candid
UNIO Candid
Fragment-based:
BMRB CS-Rosetta
Rosetta-NMR (Robetta)
Template-based:
GeNMR
I-TASSER
Refinement:
Amber
Structure from chemical shifts:
Fragment-based:
WeNMR CS-Rosetta
BMRB CS-Rosetta
Homology-based:
CS23D
Simshift
Torsion angles from chemical shifts:
Preditor
TALOS
Promega- Proline
Secondary structure from chemical shifts:
CSI (via RCI server)
TALOS
MICS caps, β-turns
d2D
PECAN
Flexibility from chemical shifts:
RCI
Interactions from chemical shifts:
HADDOCK
Chemical shifts re-referencing:
Shiftcor
UNIO Shiftinspector
LACS
CheckShift
RefDB
NMR model quality:
NOEs, other restraints:
PROSESS
PSVS
RPF scores
iCing
Chemical shifts:
PROSESS
CheShift2
Vasco
iCing
RDCs:
DC
Anisofit
Pseudocontact shifts:
Anisofit
Protein geomtery:
Resolution-by-Proxy
PROSESS
What-If
iCing
PSVS
MolProbity
SAVES2 or SAVES4
Vadar
Prosa
ProQ
MetaMQAPII
PSQS
Eval123D
STAN
Ramachandran Plot
Rampage
ERRAT
Verify_3D
Harmony
Quality Control Check
NMR spectrum prediction:
FANDAS
MestReS
V-NMR
Flexibility from structure:
Backbone S2
Methyl S2
B-factor
Molecular dynamics:
Gromacs
Amber
Antechamber
Chemical shifts prediction:
From structure:
Shiftx2
Sparta+
Camshift
CH3shift- Methyl
ArShift- Aromatic
ShiftS
Proshift
PPM
CheShift-2- Cα
From sequence:
Shifty
Camcoil
Poulsen_rc_CS
Disordered proteins:
MAXOCC
Format conversion & validation:
CCPN
From NMR-STAR 3.1
Validate NMR-STAR 3.1
NMR sample preparation:
Protein disorder:
DisMeta
Protein solubility:
camLILA
ccSOL
Camfold
camGroEL
Zyggregator
Isotope labeling:
UPLABEL
Solid-state NMR:
sedNMR


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Old 03-17-2007, 03:12 AM
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Default Metabonomics PostDoc

Post-Doctoral Associate

Bruker BioSpin has an immediate opening for a Postdoctoral Associate in a joint position between our NMR Division in Billerica, MA and Pfizer Global Research and Development in Groton, CT. This is a two year position. This talented and innovative individual will develop and optimize NMR-based metabolic profiling (metabon(l)omics) methods in biofluids, tissue extracts and tissues. Responsibilities will include protocol and method development; data acquisition; processing and analysis, identification of novel biomarkers, metabolic pathway elucidation and assist in the design and development of accessories for metabolic profiling. Candidate will spend time on both Pfizer and Bruker facilities and attend all necessary training.

Bruker BioSpin is dedicated to designing, manufacturing and distributing life science tools based on magnetic resonance. Bruker BioSpin systems, accessories and software embrace a full range of applications. We offer the most comprehensive set of technology platforms including nuclear magnetic resonance (NMR), electron paramagnetic resonance (EPR), and magnetic resonance imaging (MRI). Bruker BioSpin is an equal opportunity, affirmative action employer.

Pfizer Inc, number one pharmaceutical company, has a remarkable portfolio of medicines, the largest and most widely prescribed in the world, with innovative treatment approaches to nearly every major disease including infectious diseases, cardiovascular disease, depression, allergy, sexual health, and many others.

Job Requirements:

Ph.D. in Biochemistry, Chemistry or a related discipline or the equivalent

Experience with Metabolic Profiling using NMR Spectroscopy

Thorough understanding of scientific data analysis using statistical techniques

Excellent oral and written communication skills

Excellent organizational skills

If interested please contact:

KLC – BrukerJob1226

Bruker BioSpin

15 Fortune Drive

Manning Park

Billerica, MA 01821

USA

brukerjobs.cp1226@bruker-biospin.com
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