1 x Postdoc and 2 x Ph.D. positions in Biomolecular NMR at the Max Planck Institute, Göttingen

1 x Postdoc and 2 x Ph.D. positions in Biomolecular NMR at the MPI in Göttingen are available in the field of high-resolution PROTEIN NMR SPECTROSCOPY. The positions focus on three projects:

1) Characterization of the structure and dynamics of SOLUBLE OLIGOMERS that play an important role in several NEURODEGENERATIVE DISEASES, such as Parkinson and Alzheimer disease (PostDoc with proven experience in biomolecular NMR).
2) Characterization of PROTEIN-PROTEIN INTERACTIONS important for mitochondrial protein import. This involves structure determination of soluble proteins and of INTEGRAL MEMBRANE PROTEINS (Ph.D.).
3) Development of novel BIOINFORMATICS tools for NMR-based structural biology. The aim of the project is to further develop the PALES method (Zweckstetter, Nature Protocols 2008) to predict residual dipolar couplings from a given 3D structure. The project requires experience in C programming. NMR and/or biochemical knowledge is advantageous (PhD. or PostDoc).

An excellent environment is available for training in the area of biomolecular NMR spectroscopy. The Max Planck Institute for Biophysical Chemistry, Göttingen, is one of the top research institutes in Germany. The NMR center at the MPI for Biophysical Chemistry houses numerous, state-of-the-art NMR spectrometers from 400 to 900 MHz for both solution and solid-state NMR spectroscopy. In addition, a fully equipped laboratory for production of
recombinant proteins is available.

Applicants are desired with experience in NMR-spectroscopy and biochemistry. The Ph.D. positions (BAT IIa/2) are limited for two years but can be extended for an additional year. The postdoc position (BAT IIa) is available for three years.

Interested applicants should send a CV and contact information for two references to:
Dr. Markus Zweckstetter
Max Planck Institute for Biophysical Chemistry
NMR based Structural Biology (Head: Prof. Griesinger)
Am Fassberg 11, D-37077 Göttingen
Tel.: ++49-551-201-2220
Fax: ++49-551-201-2202
Email: mzwecks@gwdg.de

http://www.icmrbs2008.org/Portals/0/...r-July2008.pdf

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