A microfluidic device that can generate polarised xenon-129 gas and detect it by nuclear magnetic resonance, NMR, spectroscopy at tiny concentrations has been developed by an international team. The device could give a noble boost to biomedical analysis and medical imaging.
Nanoemulsion Contrast Agents with Sub-picomolar Sensitivity for Xenon NMR
From The DNP-NMR Blog:
Nanoemulsion Contrast Agents with Sub-picomolar Sensitivity for Xenon NMR
Stevens, T.K., R.M. Ramirez, and A. Pines, Nanoemulsion Contrast Agents with Sub-picomolar Sensitivity for Xenon NMR. J. Am. Chem. Soc., 2013. 135(26): p. 9576-9579.
http://dx.doi.org/10.1021/ja402885q
nmrlearner
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11-21-2013 01:14 AM
Nanoemulsion Contrast Agents with Sub-picomolar Sensitivityfor Xenon NMR
Nanoemulsion Contrast Agents with Sub-picomolar Sensitivityfor Xenon NMR
Todd K. Stevens, R. Matthew Ramirez and Alexander Pines
http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/jacsat/0/jacsat.ahead-of-print/ja402885q/aop/images/medium/ja-2013-02885q_0003.gif
Journal of the American Chemical Society
DOI: 10.1021/ja402885q
http://feeds.feedburner.com/~ff/acs/jacsat?d=yIl2AUoC8zA
http://feeds.feedburner.com/~r/acs/jacsat/~4/tOmAQoYFsGk
nmrlearner
Journal club
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06-19-2013 08:08 AM
Handheld cancer detection: Microfluidics meets NMR
Handheld cancer detection: Microfluidics meets NMR
http://www.spectroscopynow.com/common/images/thumbnails/13ef060ff6a.jpgA handheld device first developed for cancer diagnosis has been adapted to rapidly diagnose tuberculosis (TB) and other bacterial infections. Two papers appearing in the journals Nature Communications and Nature Nanotechnology describe the portable systems that bring together microfluidics technology and NMR.
Read the rest at Spectroscopynow.com
nmrlearner
General
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06-01-2013 02:03 PM
Insulin boost: Definitive speculation
Insulin boost: Definitive speculation
http://www.spectroscopynow.com/common/images/thumbnails/13c29eaa1ae.jpgAfter decades of speculation about exactly how insulin interacts with cells, an international group of scientists (led by NMR pioneer Michael Weiss) has at last demonstrated a mode of action that shows how insulin binds to the cell to allow the cell to transform sugar into energy - and how the insulin molecule then changes shape as a result of this connection.
Source: Spectroscopynow.com
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General
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02-03-2013 08:49 AM
Biosimilars to boost India's growth prospects in the next 5 years - pharmabiz.com
<img alt="" height="1" width="1" />
Biosimilars to boost India's growth prospects in the next 5 years
pharmabiz.com
And in technology space one can look for recombinant DNA technology, monoclonal antibodies technologies, protein sequencing, bioassay, chromatography, nuclear magnetic resonance and mass spectrometry. For the Indian firms to gain a big share in the ...
Biosimilars to boost India's growth prospects in the next 5 years - pharmabiz.com
More...
nmrlearner
Online News
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01-22-2013 08:58 AM
Discovery of plant proteins may boost agricultural yields, biofuel ... - R & D Magazine
Discovery of plant proteins may boost agricultural yields, biofuel ... - R & D Magazine
<img alt="" height="1" width="1" />
Discovery of plant proteins may boost agricultural yields, biofuel ...
R & D Magazine
They dubbed these fatty-acid binding proteins FAP1, FAP2, and FAP3. ... next week of a new 0.75-mm solid state nuclear magnetic resonance (NMR) probe.
and more »
Read here
nmrlearner
Online News
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06-13-2012 11:34 AM
[NMR paper] Dynamics of xenon binding inside the hydrophobic cavity of pseudo-wild-type bacteriophage T4 lysozyme explored through xenon-based NMR spectroscopy.
Dynamics of xenon binding inside the hydrophobic cavity of pseudo-wild-type bacteriophage T4 lysozyme explored through xenon-based NMR spectroscopy.
Related Articles Dynamics of xenon binding inside the hydrophobic cavity of pseudo-wild-type bacteriophage T4 lysozyme explored through xenon-based NMR spectroscopy.
J Am Chem Soc. 2005 Aug 24;127(33):11676-83
Authors: Desvaux H, Dubois L, Huber G, Quillin ML, Berthault P, Matthews BW
Wild-type bacteriophage T4 lysozyme contains a hydrophobic cavity with binding properties that have been...
Xenon boost: Medical microfluidics
A microfluidic device that can generate polarised xenon-129 gas and detect it by nuclear magnetic resonance, NMR, spectroscopy at tiny concentrations has been developed by an international team. The device could give a noble boost to biomedical analysis and medical imaging.
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