Proton NMR spectroscopy and energy dispersive X-ray fluorescence (EDXRF) spectroscopy have been used to analyse snake oil, elixirs, panaceas and other quackery found in medicines prescribed from the 18th century onwards. It turns out that many of these often-patented nostrums contained highly dangerous levels of toxic elements including arsenic, mercury and lead, as well as cocaine, heroin and high levels of alcohol.
[NMR paper] Three-dimensional structure of the RGD-containing snake toxin albolabrin in solution,
Three-dimensional structure of the RGD-containing snake toxin albolabrin in solution, based on 1H NMR spectroscopy and simulated annealing calculations.
Related Articles Three-dimensional structure of the RGD-containing snake toxin albolabrin in solution, based on 1H NMR spectroscopy and simulated annealing calculations.
Int J Pept Protein Res. 1996 Sep;48(3):220-8
Authors: Smith KJ, Jaseja M, Lu X, Williams JA, Hyde EI, Trayer IP
Albolabrin is a snake toxin that contains a RGD-(Arg-Gly-Asp) sequence motif and competes with fibrinogen to bind...
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[NMR paper] Proton NMR assignments and secondary structure of the snake venom protein echistatin.
Proton NMR assignments and secondary structure of the snake venom protein echistatin.
Related Articles Proton NMR assignments and secondary structure of the snake venom protein echistatin.
Biochemistry. 1991 Dec 17;30(50):11625-36
Authors: Chen Y, Pitzenberger SM, Garsky VM, Lumma PK, Sanyal G, Baum J
The snake venom protein echistatin is a potent inhibitor of platelet aggregation. The inhibitory properties of echistatin have been attributed to the Arg-Gly-Asp sequence at residues 24-26. In this paper, sequence-specific nuclear magnetic...
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08-21-2010 11:12 PM
[NMR paper] Proton NMR assignments and secondary structure of the snake venom protein echistatin.
Proton NMR assignments and secondary structure of the snake venom protein echistatin.
Related Articles Proton NMR assignments and secondary structure of the snake venom protein echistatin.
Biochemistry. 1991 Dec 17;30(50):11625-36
Authors: Chen Y, Pitzenberger SM, Garsky VM, Lumma PK, Sanyal G, Baum J
The snake venom protein echistatin is a potent inhibitor of platelet aggregation. The inhibitory properties of echistatin have been attributed to the Arg-Gly-Asp sequence at residues 24-26. In this paper, sequence-specific nuclear magnetic...
Panacea: Liquid grace or toxic snake oil?
Proton NMR spectroscopy and energy dispersive X-ray fluorescence (EDXRF) spectroscopy have been used to analyse snake oil, elixirs, panaceas and other quackery found in medicines prescribed from the 18th century onwards. It turns out that many of these often-patented nostrums contained highly dangerous levels of toxic elements including arsenic, mercury and lead, as well as cocaine, heroin and high levels of alcohol.
Linear Mode
