A new modelling technique for real-time tracking of metabolic reactions in tumours has been developed by UK researchers. The system based on a simplified computer model of nuclear magnetic resonance spectra could allow oncologists to assess how well their prescribed treatment, whether chemotherapy, radiotherapy or an immunological treatment is progressing without surgical intervention nor the need for regular biopsies.
[NMR900 blog] Review in Progress in Nuclear Magnetic Resonance Spectroscopy
Review in Progress in Nuclear Magnetic Resonance Spectroscopy
J.L. Kitevski-LeBlanca and R.S. Prosser, "Current Applications of 19F NMR to Studies of Protein Structure and Dynamics," Progress in Nuclear Magnetic Resonance Spectroscopy (2011) accepted. (Invited Review) http://dx.doi.org/10.1016/j.pnmrs.2011.06.003https://blogger.googleusercontent.com/tracker/8663203727601106205-2432588770174344247?l=nmr900.blogspot.com
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07-14-2011 08:55 PM
1H NMR metabolomics identification of markers of hypoxia-induced metabolic shifts in a breast cancer model system
1H NMR metabolomics identification of markers of hypoxia-induced metabolic shifts in a breast cancer model system
Abstract Hypoxia can promote invasive behavior in cancer cells and alters the response to therapeutic intervention as a result of changes in the expression many genes, including genes involved in intermediary metabolism. Although metabolomics technologies are capable of simultaneously measuring a wide range of metabolites in an untargeted manner, these methods have been relatively under utilized in the study of cancer cell responses to hypoxia. Thus, 1H NMR metabolomics was...
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03-09-2011 04:19 AM
(1)H NMR metabolomics identification of markers of hypoxia-induced metabolic shifts in a breast cancer model system.
(1)H NMR metabolomics identification of markers of hypoxia-induced metabolic shifts in a breast cancer model system.
(1)H NMR metabolomics identification of markers of hypoxia-induced metabolic shifts in a breast cancer model system.
J Biomol NMR. 2011 Mar 4;
Authors: Weljie AM, Bondareva A, Zang P, Jirik FR
Hypoxia can promote invasive behavior in cancer cells and alters the response to therapeutic intervention as a result of changes in the expression many genes, including genes involved in intermediary metabolism. Although metabolomics...
New NMR cancer model: Tracking progress
A new modelling technique for real-time tracking of metabolic reactions in tumours has been developed by UK researchers. The system based on a simplified computer model of nuclear magnetic resonance spectra could allow oncologists to assess how well their prescribed treatment, whether chemotherapy, radiotherapy or an immunological treatment is progressing without surgical intervention nor the need for regular biopsies.
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