The African pin cushion plant produces large quantities of analgesic compounds...now NMR has demonstrated that one of the primary components is chemically identical to the well-known, synthetic opioid painkiller Tramadol.
[U. of Ottawa NMR Facility Blog] The Major Constituents of Natural Gas
The Major Constituents of Natural Gas
The major constituent of natural gas is methane however, other gaseous hydrocarbons are also present. One way to identify other components is to dissolve some natural gas in a solvent and examine the 1H NMR spectrum. The spectrum in the figure below was acquired on a sample prepared by bubbling natural gas through benzene-d6 for several minutes. The spectrum clearly shows the presence of methane, ethane, propane and water.http://1.bp.blogspot.com/-q-r6TSTHCdk/T3RrTY7dVUI/AAAAAAAAA8A/lYTb4acZIQU/s400/natural_gas.jpg The spectrum also indicated other...
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03-29-2012 10:11 PM
Configurational assignment of D- and L-isovalines in intact, natural, and synthetic p
Configurational assignment of D- and L-isovalines in intact, natural, and synthetic peptides by 2D-NMR spectroscopy.
Related Articles Configurational assignment of D- and L-isovalines in intact, natural, and synthetic peptides by 2D-NMR spectroscopy.
Chem Biodivers. 2010 Jun;7(6):1612-24
Authors: De Zotti M, Schievano E, Mammi S, Kaptein B, Broxterman QB, Singh SB, Brückner H, Toniolo C
We investigated, by means of 2D-NMR, the naturally occurring and chemically synthesized 16-mer integramides A and B, which belong to a group of bioactive, fungal...
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10-22-2010 04:33 PM
[NMR paper] 1H-NMR-derived secondary structure and overall fold of a natural anatoxin from the sc
1H-NMR-derived secondary structure and overall fold of a natural anatoxin from the scorpion Androctonus australis hector.
http://www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--www3.interscience.wiley.com-aboutus-images-wiley_interscience_pubmed_logo_FREE_120x27.gif Related Articles 1H-NMR-derived secondary structure and overall fold of a natural anatoxin from the scorpion Androctonus australis hector.
Eur J Biochem. 1997 Aug 1;247(3):1118-26
Authors: Blanc E, Hassani O, Meunier S, Mansuelle P, Sampieri F, Rochat H, Darbon H
The venom of the...
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08-22-2010 05:08 PM
[NMR paper] CD and NMR structural characterization of ceratotoxins, natural peptides with antimic
CD and NMR structural characterization of ceratotoxins, natural peptides with antimicrobial activity.
Related Articles CD and NMR structural characterization of ceratotoxins, natural peptides with antimicrobial activity.
Biopolymers. 1996 Nov;39(5):653-64
Authors: Ragona L, Molinari H, Zetta L, Longhi R, Marchini D, Dallai R, Bernini LF, Lozzi L, Scarselli M, Niccolai N
Antibacterial properties of the secretion from the female reproductive accessory glands of medfly Ceratitis capitata are mostly ascribed to the presence of two peptides,...
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08-22-2010 02:20 PM
[NMR paper] 1H- and natural abundance 15N-NMR studies of a derivative of a rabies glycoprotein fr
1H- and natural abundance 15N-NMR studies of a derivative of a rabies glycoprotein fragment.
Related Articles 1H- and natural abundance 15N-NMR studies of a derivative of a rabies glycoprotein fragment.
Biopolymers. 1991 May;31(6):713-23
Authors: Molinari H, Consonni R, Pegna M, Zetta L, Neri P, Niccolai N, Bonci A, Lozzi L, Rustici M, Scarselli M
Using a combination of one- and two-dimensional methods, 1H- and 15N-nmr spectroscopy has been employed to perform the complete assignment and the structural determination of the immunogenic...
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08-21-2010 11:16 PM
[NMR paper] Assignment of the natural abundance 13C spectrum of proteins using 13C 1H-detected he
Assignment of the natural abundance 13C spectrum of proteins using 13C 1H-detected heteronuclear multiple-bond correlation NMR spectroscopy: structural information and stereospecific assignments from two- and three-bond carbon-hydrogen coupling constants.
Related Articles Assignment of the natural abundance 13C spectrum of proteins using 13C 1H-detected heteronuclear multiple-bond correlation NMR spectroscopy: structural information and stereospecific assignments from two- and three-bond carbon-hydrogen coupling constants.
Biochemistry. 1991 Oct 29;30(43):10457-66
...
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08-21-2010 11:12 PM
[NMR paper] Assignment of the natural abundance 13C spectrum of proteins using 13C 1H-detected he
Assignment of the natural abundance 13C spectrum of proteins using 13C 1H-detected heteronuclear multiple-bond correlation NMR spectroscopy: structural information and stereospecific assignments from two- and three-bond carbon-hydrogen coupling constants.
Related Articles Assignment of the natural abundance 13C spectrum of proteins using 13C 1H-detected heteronuclear multiple-bond correlation NMR spectroscopy: structural information and stereospecific assignments from two- and three-bond carbon-hydrogen coupling constants.
Biochemistry. 1991 Oct 29;30(43):10457-66
...
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08-21-2010 11:12 PM
[NMR software blog] Natural Products
Natural Products
http://1.bp.blogspot.com/_ROkYShLRKqA/SteNWieFqCI/AAAAAAAAARk/qKuAY5zIiGo/s400/antiphase.png
A reader asked me: "What is the shape of a 2-D peak?" and my answer was: "Exponential! (in time domain)". This is all you need to know, I think. The picture should help, as always. If you are reading this blog, it means that you have something like a computer. Even the iPhone is a computer (you can run programs on it) and can display my blog. I suspect, however, that you have a better computer, like I do.
You can use your computer to run simulations and more: you can ask it to...
Natural synthetic: Analgesic unearthed
The African pin cushion plant produces large quantities of analgesic compounds...now NMR has demonstrated that one of the primary components is chemically identical to the well-known, synthetic opioid painkiller Tramadol.
Linear Mode
