Nuclear magnetic resonance spectroscopy has been used to demonstrate how one segment of an important regulatory protein, nucleophosmin 1 (NPM1), helps it to fulfil several roles, including tumour suppression, according to researchers at St Jude Children's Research Hospital, Memphis, Tennessee and the Medical Research Council Laboratory of Molecular Biology, in Cambridge, UK. The findings could have implications for the development of novel anticancer drugs.
Multitasking protein: Nucleophosmin 1 - spectroscopyNOW.com
Multitasking protein: Nucleophosmin 1 - spectroscopyNOW.com
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Multitasking protein: Nucleophosmin 1
spectroscopyNOW.com
Protein function follows form, which is derived from the order of amino acids in the protein chain. It was previously assumed that the NPM1 segment was always folded into a highly ordered five-sided structure called a pentamer. However, NMR ...
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Multitasking protein: Nucleophosmin 1
Nuclear magnetic resonance spectroscopy has been used to demonstrate how one segment of an important regulatory protein, nucleophosmin 1 (NPM1), helps it to fulfil several roles, including tumour suppression, according to researchers at St Jude Children's Research Hospital, Memphis, Tennessee and the Medical Research Council Laboratory of Molecular Biology, in Cambridge, UK. The findings could have implications for the development of novel anticancer drugs.
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