Fluorine pharma: Quality control by NMR

		BioNMR > Educational resources > General
Fluorine pharma: Quality control by NMR

Webservers

NMR processing:

MDD

NMR assignment:

Backbone:

Side-chains:

NOEs:

Structure from NMR restraints:

Ab initio:

Fragment-based:

Rosetta-NMR (Robetta)

Template-based:

GeNMR

I-TASSER

Refinement:

Amber

Structure from chemical shifts:

Fragment-based:

Homology-based:

Torsion angles from chemical shifts:

Preditor

TALOS

Promega- Proline

Secondary structure from chemical shifts:

CSI (via RCI server)

TALOS

MICS caps, β-turns

d2D

PECAN

Flexibility from chemical shifts:

RCI

Interactions from chemical shifts:

HADDOCK

Chemical shifts re-referencing:

NMR model quality:

NOEs, other restraints:

Chemical shifts:

RDCs:

Pseudocontact shifts:

Protein geomtery:

SAVES2 or SAVES4

Quality Control Check

NMR spectrum prediction:

FANDAS

MestReS

V-NMR

Flexibility from structure:

Backbone S2

Methyl S2

B-factor

Molecular dynamics:

Gromacs

Amber

Antechamber

Chemical shifts prediction:

From structure:

Shiftx2

Sparta+

Camshift

CH3shift- Methyl

ArShift- Aromatic

ShiftS

Proshift

PPM

CheShift-2- Cα

From sequence:

Shifty

Camcoil

Poulsen_rc_CS

Disordered proteins:

MAXOCC

Format conversion & validation:

CCPN

From NMR-STAR 3.1

Validate NMR-STAR 3.1

NMR sample preparation:

Protein disorder:

DisMeta

Protein solubility:

Isotope labeling:

Solid-state NMR:

Thread Tools

Search this Thread

Rate Thread

Display Modes

12-01-2017, 08:23 AM

nmrlearner

Senior Member

Join Date: Jan 2005

Posts: 23,734

Points: 193,617, Level: 100

Level up: 0%, 0 Points needed

Activity: 50.7%

Last Achievements

Award-Showcase

NMR Credits: 0

NMR Points: 193,617

Downloads: 0

Uploads: 0

Fluorine pharma: Quality control by NMR

Fluorine pharma: Quality control by NMR

Routine analysis and quality control of fluorine-containing pharmaceuticals could now be possible with the application of the relatively simple and straightforward technique of fluorine-19 nuclear magnetic resonance (NMR) spectroscopy, according to researchers in Kenya and Germany.

Read the rest at Spectroscopynow.com

Did you find this post helpful?

Similar Threads
Thread	Thread Starter	Forum	Replies	Last Post
CIL partners to provide more isotope-labeled proteins to pharma - OutSourcing-Pharma.com CIL partners to provide more isotope-labeled proteins to pharma - OutSourcing-Pharma.com <img alt="" height="1" width="1" /> CIL partners to provide more isotope-labeled proteins to pharma OutSourcing-Pharma.com "Nexomics success in developing techniques to determine protein structure using Nuclear Magnetic Resonance (NMR) spectroscopy nicely complements CIL's mission to offer isotope enriched reagents used to produce labeled recombinant protein. Read here	nmrlearner	Online News	0	01-30-2014 05:38 PM
Low-Field Permanent Magnets for Industrial Process and Quality Control Low-Field Permanent Magnets for Industrial Process and Quality Control Publication date: Available online 30 September 2013 Source:Progress in Nuclear Magnetic Resonance Spectroscopy</br> Author(s): J. Mitchell , L.F. Gladden , T.C. Chandrasekera , E.J. Fordham</br> In this review we focus on the technology associated with lowfield NMR. We present the current state-of-the-art in low-field NMR hardware and experiments, considering general magnet designs, rf performance, data processing and interpretation. We provide guidance on obtaining the optimum results from...	nmrlearner	Journal club	0	09-30-2013 03:48 PM
Scientists Discover Structure of Protein Essential for Quality Control, Nerve ... - Bioscience Technology <img alt="" height="1" width="1" /> Scientists Discover Structure of Protein Essential for Quality Control, Nerve ... Bioscience Technology Ltn1 was deemed too large for its structure to be determined by current nuclear magnetic resonance (NMR) technology, and, as the scientists know now, too flexible to allow the highly regular crystalline packing needed by X-ray crystallographers. â??It's ... Scientists Discover Structure of Protein Essential for Quality Control, Nerve ... - Bioscience Technology More...	nmrlearner	Online News	0	01-15-2013 11:39 PM
Scientists Discover Structure of Protein Essential for Quality Control, Nerve ... - Science Daily (press release) Scientists Discover Structure of Protein Essential for Quality Control, Nerve ... - Science Daily (press release) <img alt="" height="1" width="1" /> Scientists Discover Structure of Protein Essential for Quality Control, Nerve ... Science Daily (press release) Ltn1 was deemed too large for its structure to be determined by current nuclear magnetic resonance (NMR) technology, and, as the scientists know now, too flexible to allow the highly regular crystalline packing needed by X-ray crystallographers. "It's ... and more » Read here	nmrlearner	Online News	0	01-15-2013 10:56 AM
[NMR tweet] NMR of Aloe Vera for Quality Control: NMR of Aloe Vera, Exova provides analysis by nu NMR of Aloe Vera for Quality Control: NMR of Aloe Vera, Exova provides analysis by nuclear magnetic resonance with... http://bit.ly/aNlj0c Published by RadiantEuphoria (Radiant Euphoria) on 2010-10-25T02:43:37Z Source: Twitter	nmrlearner	Twitter NMR	0	10-25-2010 02:55 AM
Real-time NMR Studies of the Folding & Mechanisms of Protein Quality Control Machiner Real-time NMR Studies of the Folding & Mechanisms of Protein Quality Control Machineries * In the context of a project funded by European Research Council, two postdoctoral positions are available at the Structural Biology Institute in Grenoble (France) to study by real-time NMR the Folding & Mechanisms of Protein Quality Control (PQC) Machineries. Selected candidates will use latest NMR technologies developed at IBS to characterize self-assembly and functionally important structural rearrangements of large PQC machineries isolated at IBS. * The laboratory host… More...	nmrlearner	Job marketplace	0	09-11-2010 01:25 AM
PhD position - Quality Control of Therapeutic Proteins by NMR - IGBMC, Illkirch, France The ICMRBS website has an advert for a PhD studentship based at the IGBMC Biomolecular NMR group in France: http://www.icmrbs2008.org/%5CPortals%5C0%5CPhD%20Position_QC%20of%20Therapeutic%20Proteins%20by%20NMR.pdf	Cameron	Job marketplace	0	09-21-2008 11:41 AM

« Previous Thread | Next Thread »

Posting Rules
You may not post new threads You may not post replies You may not post attachments You may not edit your posts BB code is On Smilies are On [IMG] code is On HTML code is Off Trackbacks are Off Pingbacks are Off Refbacks are Off