A novel NMR technique developed by researchers at the University of Toronto Scarborough, Canada, can for the first time obtain undistorted high-resolution profiles of the molecules and metabolites present within a living organism.
[NMR paper] Metabolic profiling in kidneys of Atlantic salmon infected with Aeromonas salmonicida based on (1)H NMR.
Metabolic profiling in kidneys of Atlantic salmon infected with Aeromonas salmonicida based on (1)H NMR.
Related Articles Metabolic profiling in kidneys of Atlantic salmon infected with Aeromonas salmonicida based on (1)H NMR.
Fish Shellfish Immunol. 2016 Aug 27;
Authors: Liu PF, Du Y, Meng L, Li X, Liu Y
Abstract
Aeromonas salmonicida, an important pathogenic bacterium which induces furunculosis, is globally causing increased risks in Atlantic salmon (Salmo salar) farming. Although the kidney is the main target organ of A....
nmrlearner
Journal club
0
09-01-2016 07:21 PM
[NMR paper] NMR-Based Metabolic Profiling Reveals Neurochemical Alterations in the Brain of Rats Treated with Sorafenib.
NMR-Based Metabolic Profiling Reveals Neurochemical Alterations in the Brain of Rats Treated with Sorafenib.
http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--production.springer.de-OnlineResources-Logos-springerlink.gif Related Articles NMR-Based Metabolic Profiling Reveals Neurochemical Alterations in the Brain of Rats Treated with Sorafenib.
Neurotox Res. 2015 Nov;28(4):290-301
Authors: Du C, Shao X, Zhu R, Li Y, Zhao Q, Fu D, Gu H, Kong J, Luo L, Long H, Deng P, Wang H, Hu C, Zhao Y, Cen X
Abstract
...
nmrlearner
Journal club
0
07-22-2016 02:21 PM
[NMR paper] Malignancy-associated metabolic profiling of human glioma cell lines using 1H NMR spectroscopy.
Malignancy-associated metabolic profiling of human glioma cell lines using 1H NMR spectroscopy.
Related Articles Malignancy-associated metabolic profiling of human glioma cell lines using 1H NMR spectroscopy.
Mol Cancer. 2014 Aug 27;13(1):197
Authors: Shao W, Gu J, Huang C, Liu D, Huang H, Huang Z, Lin Z, Yang W, Liu K, Lin D, Ji T
Abstract
BACKGROUND: Ambiguity in malignant transformation of glioma has made prognostic diagnosis very challenging. Tumor malignant transformation is closely correlated with specific alterations...
nmrlearner
Journal club
0
08-29-2014 05:36 PM
Journal Highlight: 1H NMR based metabolic profiling in Crohn's disease by random forest methodology
Journal Highlight: 1H NMR based metabolic profiling in Crohn's disease by random forest methodology
http://www.spectroscopynow.com/common/images/thumbnails/146ed5b84e7.jpg1H NMR spectroscopy of the serum metabolites of patients with Crohn's disease, supported by random forest methodology, showed that valine and isoleucine are differentiating metabolites for diagnosis.
Read the rest at Spectroscopynow.com
nmrlearner
General
0
06-30-2014 11:39 PM
[NMR paper] Metabolic changes during cellular senescence investigated by proton NMR-spectroscopy.
Metabolic changes during cellular senescence investigated by proton NMR-spectroscopy.
http://www.bionmr.com//www.ncbi.nlm.nih.gov/corehtml/query/egifs/http:--linkinghub.elsevier.com-ihub-images-PubMedLink.gif Related Articles Metabolic changes during cellular senescence investigated by proton NMR-spectroscopy.
Mech Ageing Dev. 2013 Mar;134(3-4):130-8
Authors: Gey C, Seeger K
Abstract
Cellular senescence is of growing interest due to its role in tumour suppression and its contribution to organismic ageing. This cellular state can be...
nmrlearner
Journal club
0
10-01-2013 11:15 PM
Colon cancer calculated: Metabolic profiling
Colon cancer calculated: Metabolic profiling
http://www.spectroscopynow.com/common/images/thumbnails/14077d20717.jpgNuclear magnetic resonance (NMR) spectroscopy can be used to obtain a metabolic fingerprint of cancer of the bowel and so determine how far advanced the disease is, according to UK researchers.
Read the rest at Spectroscopynow.com
nmrlearner
General
0
08-15-2013 07:22 AM
Metabolic profiling of vitamin C deficiency in Guloâ??/â?? mice using proton NMR spectroscopy
Metabolic profiling of vitamin C deficiency in Guloâ??/â?? mice using proton NMR spectroscopy
Abstract Nutrient deficiencies are an ongoing problem in many populations and ascorbic acid is a key vitamin whose mild or acute absence leads to a number of conditions including the famously debilitating scurvy. As such, the biochemical effects of ascorbate deficiency merit ongoing scrutiny, and the Gulo knockout mouse provides a useful model for the metabolomic examination of vitamin C deficiency. Like humans, these animals are incapable of synthesizing ascorbic acid but with dietary...
nmrlearner
Journal club
0
03-03-2011 02:06 AM
1H NMR-based metabolic profiling reveals inherent biological variation in yeast and nematode model systems
1H NMR-based metabolic profiling reveals inherent biological variation in yeast and nematode model systems
Abstract The application of metabolomics to human and animal model systems is poised to provide great insight into our understanding of disease etiology and the metabolic changes that are associated with these conditions. However, metabolomic studies have also revealed that there is significant, inherent biological variation in human samples and even in samples from animal model systems where the animals are housed under carefully controlled conditions. This inherent biological...
Cellular signals: NMR metabolic profiling
A novel NMR technique developed by researchers at the University of Toronto Scarborough, Canada, can for the first time obtain undistorted high-resolution profiles of the molecules and metabolites present within a living organism.
Linear Mode
