The combined forces of nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry have been used in research that shows how cell metabolism affects the ability of cells to undergo a survival program called autophagy during cancer chemotherapy allowing a tumour to regrow.
[ASAP] Changes in Protein Dynamics in Escherichia coli SufS Reveal a Possible Conserved Regulatory Mechanism in Type II Cysteine Desulfurase Systems
Changes in Protein Dynamics in Escherichia coli SufS Reveal a Possible Conserved Regulatory Mechanism in Type II Cysteine Desulfurase Systems
https://pubs.acs.org/appl/literatum/publisher/achs/journals/content/bichaw/0/bichaw.ahead-of-print/acs.biochem.7b01275/20180404/images/medium/bi-2017-012754_0008.gif
Biochemistry
DOI: 10.1021/acs.biochem.7b01275
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nmrlearner
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04-06-2018 01:51 AM
Molecular Simulations Reveal an Unresolved Conformationof the Type IA Protein Kinase A Regulatory Subunit and Suggest ItsRole in the cAMP Regulatory Mechanism
Molecular Simulations Reveal an Unresolved Conformationof the Type IA Protein Kinase A Regulatory Subunit and Suggest ItsRole in the cAMP Regulatory Mechanism
http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/bichaw/0/bichaw.ahead-of-print/acs.biochem.7b00461/20170717/images/medium/bi-2017-00461q_0003.gif
Biochemistry
DOI: 10.1021/acs.biochem.7b00461
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nmrlearner
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07-18-2017 07:52 AM
[NMR paper] NMR Binding and Crystal Structure Reveal that Intrinsically-unstructured Regulatory Domain Auto-inhibits PAK4 by a Mechanism Different for that of PAK1.
NMR Binding and Crystal Structure Reveal that Intrinsically-unstructured Regulatory Domain Auto-inhibits PAK4 by a Mechanism Different for that of PAK1.
NMR Binding and Crystal Structure Reveal that Intrinsically-unstructured Regulatory Domain Auto-inhibits PAK4 by a Mechanism Different for that of PAK1.
Biochem Biophys Res Commun. 2013 Jul 19;
Authors: Wang W, Lim L, Baskaran Y, Manser E, Song J
Abstract
Six human PAK members are classified into groups I (PAKs 1-3) and II (PAK4-6). Previously, only group I PAKs were thought to be...
nmrlearner
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07-24-2013 04:52 PM
NMR-derived models of amidopyrine and its metabolites in complexes with rabbit cytochrome P450 2B4 reveal a structural mechanism of sequential N-dealkylation.
NMR-derived models of amidopyrine and its metabolites in complexes with rabbit cytochrome P450 2B4 reveal a structural mechanism of sequential N-dealkylation.
NMR-derived models of amidopyrine and its metabolites in complexes with rabbit cytochrome P450 2B4 reveal a structural mechanism of sequential N-dealkylation.
Biochemistry. 2011 Mar 29;50(12):2123-34
Authors: Roberts AG, Sjögren SE, Fomina N, Vu KT, Almutairi A, Halpert JR
To understand the molecular basis of sequential N-dealkylation by cytochrome P450 2B enzymes, we studied the binding of...
[NMR paper] 1H-NMR studies on water structures in the rat brain tissues with cerebral tumour or i
1H-NMR studies on water structures in the rat brain tissues with cerebral tumour or ischaemia.
Related Articles 1H-NMR studies on water structures in the rat brain tissues with cerebral tumour or ischaemia.
Acta Neurochir Suppl (Wien). 1990;51:125-7
Authors: Iwama T, Andoh T, Sakai N, Yamada H, Era S, Kuwata K, Sogami M, Watari H
Spin-lattice relaxation times (T1) of water protons and cross-relaxation times (T(IS)) between irradiated protein protons and observed water protons were measured to study water structure in various rat brain tissue....
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08-21-2010 10:48 PM
The NMR structure of the autophagy-related protein Atg8
The NMR structure of the autophagy-related protein Atg8
Content Type Journal Article
DOI 10.1007/s10858-010-9420-1
Authors
Hiroyuki Kumeta, Hokkaido University Laboratory of Structural Biology, Graduate School of Pharmaceutical Sciences Kita 12 Nishi 6 Kita-ku Sapporo 060-0812 Japan
Masahiro Watanabe, Hokkaido University Laboratory of Structural Biology, Graduate School of Pharmaceutical Sciences Kita 12 Nishi 6 Kita-ku Sapporo 060-0812 Japan
Hitoshi Nakatogawa, Tokyo Institute of Technology Integrated Research Institute Yokohama 226-8503 Japan
Autophagy: NMR and MS reveal tumour regrowth mechanism
The combined forces of nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry have been used in research that shows how cell metabolism affects the ability of cells to undergo a survival program called autophagy during cancer chemotherapy allowing a tumour to regrow.
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