Understanding NMR Spectroscopy
Understanding NMR Spectroscopy
http://www.spectroscopynow.com/common/images/thumbnails/sepspec10366education.jpgJames Keeler, Editor-in-Chief of Magnetic Resonance in Chemistry, discusses the high-resolution NMR of liquid samples, concentratring exclusively on spin-half nuclei (mainly 1H and 13C). It is aimed at people who are familiar with the use of routine NMR for structure determination and who wish to deepen their understanding of just exactly how NMR experiments work.
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02-03-2013 09:28 AM
Understanding small-molecule binding to MDM2: insights into structural effects of isoindolinone inhibitors from NMR spectroscopy.
Understanding small-molecule binding to MDM2: insights into structural effects of isoindolinone inhibitors from NMR spectroscopy.
Understanding small-molecule binding to MDM2: insights into structural effects of isoindolinone inhibitors from NMR spectroscopy.
Chem Biol Drug Des. 2011 May;77(5):301-8
Authors: Riedinger C, Noble ME, Wright DJ, Mulks F, Hardcastle IR, Endicott JA, McDonnell JM
The interaction between murine double minute (MDM2) and p53 is a major target in anticancer drug design. Several potent compound series, including the nutlins...
[NMR paper] Time dependence of aggregation in crystallizing lysozyme solutions probed using NMR s
Time dependence of aggregation in crystallizing lysozyme solutions probed using NMR self-diffusion measurements.
Related Articles Time dependence of aggregation in crystallizing lysozyme solutions probed using NMR self-diffusion measurements.
Biophys J. 2001 Mar;80(3):1585-90
Authors: Price WS, Tsuchiya F, Arata Y
The time dependence of aggregation in supersaturated lysozyme solutions was studied using pulsed-gradient spin-echo NMR diffusion measurements as a function of lysozyme concentration at pH 6.0 and 298 K in the presence of 0.5 M NaCl....
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11-19-2010 08:32 PM
[NMR paper] The hydration of proteins in solutions by self-diffusion coefficients. NMR study.
The hydration of proteins in solutions by self-diffusion coefficients. NMR study.
Related Articles The hydration of proteins in solutions by self-diffusion coefficients. NMR study.
Biochim Biophys Acta. 1996 Apr 17;1289(3):312-4
Authors: Baranowska HM, Olszewski KJ
The hydration of the globular (lysozyme, albumin) and fibrillar (fibrinogen) proteins in solution has been determined from the measurements of the self-diffusion coefficient by NMR pulsed gradient method. It has been concluded that the concentration dependencies of the...
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08-22-2010 02:27 PM
[NMR paper] NMR spectroscopy of hydroxyl protons in aqueous solutions of peptides and proteins.
NMR spectroscopy of hydroxyl protons in aqueous solutions of peptides and proteins.
Related Articles NMR spectroscopy of hydroxyl protons in aqueous solutions of peptides and proteins.
J Biomol NMR. 1992 Sep;2(5):447-65
Authors: Liepinsh E, Otting G, Wüthrich K
Hydroxyl groups of serine and threonine, and to some extent also tyrosine are usually located on or near the surface of proteins. NMR observations of the hydroxyl protons is therefore of interest to support investigations of the protein surface in solution, and knowledge of the...
Understanding NMR Spectroscopy - The Solutions and Figures
This is the Solutions Manual to the exercises set in "Understanding NMR Spectroscopy" by James Keeler (Wiley, 2010 & 2005).
Linear Mode
