James Keeler, Editor-in-Chief of Magnetic Resonance in Chemistry, discusses the high-resolution NMR of liquid samples, concentratring exclusively on spin-half nuclei (mainly 1H and 13C). It is aimed at people who are familiar with the use of routine NMR for structure determination and who wish to deepen their understanding of just exactly how NMR experiments work.
Understanding Protein Crystallization Growth at the University of ... - Azom.com
Understanding Protein Crystallization Growth at the University of ... - Azom.com
http://www.bionmr.com//nt2.ggpht.com/news/tbn/YvGbSkpEZpDV7M/6.jpg
Azom.com
<img alt="" height="1" width="1" />
Understanding Protein Crystallization Growth at the University of ...
Azom.com
Understanding Protein Crystallization Growth at the University of Leeds using a ... Mass Spectrometers · Nuclear Magnetic Resonance Spectroscopy (NMR) ...
nmrlearner
Online News
0
06-28-2012 07:54 AM
Understanding the radical mechanism of lipoxygenases using 31P NMR spin trapping.
Understanding the radical mechanism of lipoxygenases using 31P NMR spin trapping.
Understanding the radical mechanism of lipoxygenases using 31P NMR spin trapping.
Bioorg Med Chem. 2011 May 1;19(9):3022-8
Authors: Zoia L, Perazzini R, Crestini C, Argyropoulos DS
Abstract
In this paper, we use our quantitative (31)P NMR spin trapping methods, already developed for simple oxygen- and carbon-centered radicals, to understand the radical intermediates generated by enzymatic systems and more specifically lipoxygenases. Our methodology...
nmrlearner
Journal club
0
08-25-2011 04:10 PM
Understanding small-molecule binding to MDM2: insights into structural effects of isoindolinone inhibitors from NMR spectroscopy.
Understanding small-molecule binding to MDM2: insights into structural effects of isoindolinone inhibitors from NMR spectroscopy.
Understanding small-molecule binding to MDM2: insights into structural effects of isoindolinone inhibitors from NMR spectroscopy.
Chem Biol Drug Des. 2011 May;77(5):301-8
Authors: Riedinger C, Noble ME, Wright DJ, Mulks F, Hardcastle IR, Endicott JA, McDonnell JM
The interaction between murine double minute (MDM2) and p53 is a major target in anticancer drug design. Several potent compound series, including the nutlins...
nmrlearner
Journal club
0
08-05-2011 11:48 AM
[Question from NMRWiki Q&A forum] Beginner: Help understanding 3D NOESY
Beginner: Help understanding 3D NOESY
Hi, I am a person with a Computer Science background who is dealing with some NMR dataset. I am concerned with the assignment of NMR peaks from several experiments. For structure determination, I am dealing with 3D-NOESY data. I am finding it a little hard to comprehend what the several peaks mean here. I understand what the peaks in a 2D dataset like 1H-1H NOESY dataset mean but not on higher dimensions.
I do not understand the nomenclature followed in the naming of NOESY experiments because I feel a little lost in all the technical details in the...
Towards a structural understanding of the smallest known oncoprotein: Investigation o
Towards a structural understanding of the smallest known oncoprotein: Investigation of the Bovine Papillomavirus E5 protein using solution-state NMR.
Related Articles Towards a structural understanding of the smallest known oncoprotein: Investigation of the Bovine Papillomavirus E5 protein using solution-state NMR.
Biochim Biophys Acta. 2010 Nov 9;
Authors: King G, Oates J, Patel D, van den Berg HA, Dixon AM
The homo-dimeric E5 protein from Bovine Papillomavirus activates the platelet-derived growth factor ? receptor through transmembrane (TM)...