This book highlights analytical chemistry instrumentation and practices applied to the analysis of natural products and their complex mixtures, describing techniques for isolating and characterizing natural products.• Applies analytical techniques to natural products research – an area of critical importance to drug discovery• Offers a one-stop shop for most analytical methods: x-ray diffraction, NMR analysis, mass spectrometry, and chemical genetics• Includes coverage...
Sodium MRI: Methods and Applications
Sodium MRI: Methods and Applications
Publication date: Available online 6 March 2014
Source:Progress in Nuclear Magnetic Resonance Spectroscopy</br>
Author(s): Guillaume Madelin , Jae-Seung Lee , Ravinder R. Regatte , Alexej Jerschow</br>
Sodium NMR spectroscopy and MRI have become popular in recent years through the increased availability of high-field MRI scanners, advanced scanner hardware and improved methodology. Sodium MRI is being evaluated for stroke and tumor detection, for breast cancer studies, and for the assessment of osteoarthritis and muscle and...
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03-08-2014 06:52 AM
Analysis of Moisture, Fat and Protein in Cheese Products - Azom.com
Analysis of Moisture, Fat and Protein in Cheese Products - Azom.com
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Analysis of Moisture, Fat and Protein in Cheese Products
Azom.com
The SMART Trac II from CEM enables the testing of moisture and fat using TD-NMR coupled with microwave drying, which has been established as the most accurate rapid method available. The study of the entire sample on a molecular level not just the ...
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03-07-2014 05:41 AM
Hyperpolarization Methods and Applications in NMR
From The DNP-NMR Blog:
Hyperpolarization Methods and Applications in NMR
Köckenberger, W. and J. Matysik, Hyperpolarization Methods and Applications in NMR, in Encyclopedia of Spectroscopy and Spectrometry (Second Edition), L. Editor-in-Chief: John, Editor. 2010, Academic Press: Oxford. p. 963-970.
http://dx.doi.org/10.1016/B978-0-12-374413-5.00054-3
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08-21-2013 08:49 PM
[NMR paper] EC-SPE-stripline-NMR analysis of reactive products: a feasibility study.
EC-SPE-stripline-NMR analysis of reactive products: a feasibility study.
Related Articles EC-SPE-stripline-NMR analysis of reactive products: a feasibility study.
Anal Bioanal Chem. 2013 Jun 30;
Authors: Falck D, Oosthoek-de Vries AJ, Kolkman A, Lingeman H, Honing M, Wijmenga SS, Kentgens AP, Niessen WM
Abstract
Flow-through electrochemical conversion (EC) of drug-like molecules was hyphenated to miniaturized nuclear magnetic resonance spectroscopy (NMR) via on-line solid-phase extraction (SPE). After EC of the prominent p38?...
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07-03-2013 01:46 PM
Using NMR to study fast dynamics in proteins: methods and applications.
Using NMR to study fast dynamics in proteins: methods and applications.
Related Articles Using NMR to study fast dynamics in proteins: methods and applications.
Curr Opin Pharmacol. 2010 Oct 6;
Authors: Sapienza PJ, Lee AL
Proteins exist not as singular structures with precise coordinates, but rather as fluctuating bodies that move rapidly through an enormous number of conformational substates. These dynamics have important implications for understanding protein function and for structure-based drug design. NMR spectroscopy is particularly well...
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10-12-2010 02:52 PM
Biochemical disorders induced by cytotoxic marine natural products in breast cancer c
Biochemical disorders induced by cytotoxic marine natural products in breast cancer cells as revealed by proton NMR spectroscopy-based metabolomics.
Related Articles Biochemical disorders induced by cytotoxic marine natural products in breast cancer cells as revealed by proton NMR spectroscopy-based metabolomics.
Biochem Pharmacol. 2010 Oct 15;80(8):1170-9
Authors: Bayet-Robert M, Lim S, Barthomeuf C, Morvan D
Marine plants and animals are sources of a huge number of pharmacologically active compounds, some of which exhibit antineoplastic...
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10-12-2010 02:52 PM
[NMR software blog] Natural Products
Natural Products
http://1.bp.blogspot.com/_ROkYShLRKqA/SteNWieFqCI/AAAAAAAAARk/qKuAY5zIiGo/s400/antiphase.png
A reader asked me: "What is the shape of a 2-D peak?" and my answer was: "Exponential! (in time domain)". This is all you need to know, I think. The picture should help, as always. If you are reading this blog, it means that you have something like a computer. Even the iPhone is a computer (you can run programs on it) and can display my blog. I suspect, however, that you have a better computer, like I do.
You can use your computer to run simulations and more: you can ask it to...