Unlike traditional NMR textbooks for chemists, this fresh look at the topic combines theory, technology and application in a wide range of fields, targeting biochemists, medicinal chemists, and structural biologists, as well as organic chemists. The text has been developed from a one-semester graduate-level course taught by the authors at the University of Zurich, and offers numerous intuitive illustrations, training exercises and plain-language explanations of complex theory. Divided into four major...
[Stan NMR blog] A new NMR textbook for chemists
A new NMR textbook for chemists
Essential Practical NMR for Organic Chemistry by S.Richards and J.Hollerton
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03-26-2012 07:34 PM
Magneto-optical contrast in liquid-state optically detected NMR spectroscopy [Applied Physical Sciences]
Magneto-optical contrast in liquid-state optically detected NMR spectroscopy
Pagliero, D., Meriles, C. A....
Date: 2011-12-06
We use optical Faraday rotation (OFR) to probe nuclear spins in real time at high-magnetic field in a range of diamagnetic sample fluids. Comparison of OFR-detected NMR spectra reveals a correlation between the relative signal amplitude and the fluid Verdet constant, which we interpret as a manifestation of the variable detuning between the probe beam and the sample optical transitions. The analysis of chemical-shift-resolved, optically detected spectra allows...
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12-06-2011 08:04 PM
Fractional deuteration applied to biomolecular solid-state NMR spectroscopy
Fractional deuteration applied to biomolecular solid-state NMR spectroscopy
Abstract Solid-state Nuclear Magnetic Resonance can provide detailed insight into structural and dynamical aspects of complex biomolecules. With increasing molecular size, advanced approaches for spectral simplification and the detection of medium to long-range contacts become of critical relevance. We have analyzed the protonation pattern of a membrane-embedded ion channel that was obtained from bacterial expression using protonated precursors and D2O medium. We find an overall reduction of 50% in protein...
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11-24-2011 12:25 AM
[Stan NMR blog] A new NMR textbook for chemists
A new NMR textbook for chemists
Essential Practical NMR for Organic Chemistry by S.Richards and J.Hollerton
Source: Stan blog library
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01-23-2011 03:57 AM
NMR spectroscopy and surface tension measurements applied to the study of self-association of casopitant mesylate, a novel NK1 antagonist.
NMR spectroscopy and surface tension measurements applied to the study of self-association of casopitant mesylate, a novel NK1 antagonist.
NMR spectroscopy and surface tension measurements applied to the study of self-association of casopitant mesylate, a novel NK1 antagonist.
J Pharm Biomed Anal. 2011 Jan 5;54(1):48-52
Authors: Provera S, Beato S, Cimarosti Z, Turco L, Casazza A, Caivano G, Marchioro C
The aggregation behaviour of casopitant mesylate, a new NK1 antagonist drug, was investigated by means of NMR spectroscopy and surface tension...
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01-11-2011 11:27 PM
[NMR paper] Solid-state NMR spectroscopy applied to membrane proteins.
Solid-state NMR spectroscopy applied to membrane proteins.
Related Articles Solid-state NMR spectroscopy applied to membrane proteins.
Curr Opin Struct Biol. 2000 Oct;10(5):593-600
Authors: de Groot HJ
One major remaining problem in structural biology is to elucidate the structure and mechanism of function of membrane proteins. On the basis of preliminary information from genome projects, it is now estimated that up to 50,000 different membrane proteins may exist in the human being and that virtually every life process proceeds, sooner or...
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11-19-2010 08:29 PM
New book: Practical NMR Relaxation for Chemists
New book Alert:
Practical Nuclear Magnetic Resonance Relaxation for Chemistshttp://www.assoc-amazon.com/e/ir?t=bionmr-20&l=ur2&o=1
By Vladimir I. Bakhmutov (Texas A&M University). John Wiley & Sons, Ltd: Chichester, U.K. 2004. xii + 202 pp. $185.00. ISBN 0-470-09445-1.
Editorial Reviews from Amazon.com
Book DescriptionThis book demonstrates how NMR relaxation can be applied for structural diagnostics of chemical compounds, recognition of weak intermolecular interactions, determinations of internuclear distances and lengths of chemical bonds when compounds under investigation...