Retaining the excellent didactic style found in his previous bestselling works, Professor Berger has written this textbook for true beginners. He highlights around 50 of the most important experiments and explains them step-by-step, backed by questions and answers for easier learning. The result is the universal NMR cookbook: The descriptions are not instrument-specific and can be used on all NMR spectrometers, perfectly illustrating how to perform the experiments after only having studied the theory....
Two-dimensional heteronuclear saturation transfer difference NMR reveals detailed int
Two-dimensional heteronuclear saturation transfer difference NMR reveals detailed integrin αvβ6 protein-peptide interactions.
Related Articles Two-dimensional heteronuclear saturation transfer difference NMR reveals detailed integrin αvβ6 protein-peptide interactions.
Chem Commun (Camb). 2010 Sep 13;
Authors: Wagstaff JL, Vallath S, Marshall JF, Williamson RA, Howard MJ
We report the first example of peptide-protein heteronuclear two-dimensional (2D) saturation transfer difference nuclear magnetic resonance (STD NMR). This method, resulting in...
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09-15-2010 02:26 PM
[NMR paper] Detailed assessment of spatial hydrophobic and electrostatic properties of 2D NMR-der
Detailed assessment of spatial hydrophobic and electrostatic properties of 2D NMR-derived models of neurotoxin II.
Related Articles Detailed assessment of spatial hydrophobic and electrostatic properties of 2D NMR-derived models of neurotoxin II.
J Biomol Struct Dyn. 1995 Apr;12(5):971-91
Authors: Efremov RG, Golovanov AP, Vergoten G, Alix AJ, Tsetlin VI, Arseniev AS
2D NMR-derived spatial structures of neurotoxin II (NtII) and several homologous toxins in solution were assessed by comparison with their own amino acid sequences using a...
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08-22-2010 03:41 AM
Detailed, superficial approach to finding new drugs
Detailed, superficial approach to finding new drugs
An international team has used NMR spectroscopy to study neglected regions of key cell-surface proteins. They have found that these regions undergo minute conformational changes in response to drugs, a finding that could ultimately prove useful in the design of new drugs for a range of diseases.
Source: Spectroscopynow.com
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08-16-2010 03:50 AM
Nitrogen-detected CAN and CON experiments as alternative experiments for main chain N
Abstract Heteronuclear direct-detection experiments, which utilize the slower relaxation properties of low γ nuclei, such as 13C have recently been proposed for sequence-specific assignment and structural analyses of large, unstructured, and/or paramagnetic proteins. Here we present two novel 15N direct-detection experiments. The CAN experiment sequentially connects amide 15N resonances using 13Cα chemical shift matching, and the CON experiment connects the preceding 13C� nuclei. When starting from the same carbon polarization, the intensities of nitrogen signals detected in the CAN or...
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08-14-2010 04:19 AM
Guide to NOE Experiments - The ANU NMR Centre
Guide to NOE Experiments - The ANU NMR Centre
The Australian National University website provides a short guide to some of the theoretical and practical aspects of NOE experiments. Well worth a look.
50 and More Essential NMR Experiments - A Detailed Guide
Retaining the excellent didactic style found in his previous bestselling works, Professor Berger has written this textbook for true beginners. He highlights around 50 of the most important experiments and explains them step-by-step, backed by questions and answers for easier learning. The result is the universal NMR cookbook: The descriptions are not instrument-specific and can be used on all NMR spectrometers, perfectly illustrating how to perform the experiments after only having studied the 
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