Thread: NMR paper ARCHE-NOAH: NMR supersequence with five different CEST experiments for studying protein conformational dynamics
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Unread 06-08-2023, 09:28 PM
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Default ARCHE-NOAH: NMR supersequence with five different CEST experiments for studying protein conformational dynamics
ARCHE-NOAH: NMR supersequence with five different CEST experiments for studying protein conformational dynamics

An NMR NOAH-supersequence is presented consisting of five CEST experiments for studying protein backbone and side-chain dynamics by ^(15)N-CEST, carbonyl-^(13)CO-CEST, aromatic-^(13)C(ar)-CEST, ^(13)C(?)-CEST, and methyl-^(13)C(met)-CEST. The new sequence acquires the data for these experiments in a fraction of the time required for the individual experiments, saving over four days of NMR time per sample.

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