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3D Protein Structure Analysis Market - A Global and Country Analysis: Focus on Product, End User, and Region - Analysis and Forecast, 2022-2032 - GlobeNewswire
Sep 28, 2022 - 6:29 AM - by nmrlearner
nmrlearner's Avatar 3D Protein Structure Analysis Market - A Global and Country Analysis: Focus on Product, End User, and Region - Analysis and Forecast, 2022-2032 GlobeNewswire
3D Protein Structure Analysis Market - A Global and Country Analysis: Focus on Product, End User, and Region - Analysis and Forecast, 2022-2032 - GlobeNewswire
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3D Protein Structure Analysis Market - A Global and Country Analysis: Focus on Product, End User, and Region - Analysis and Forecast, 2022-2032 - Yahoo Finance
Sep 28, 2022 - 6:29 AM - by nmrlearner
nmrlearner's Avatar 3D Protein Structure Analysis Market - A Global and Country Analysis: Focus on Product, End User, and Region - Analysis and Forecast, 2022-2032 - Yahoo Finance

3D Protein Structure Analysis Market - A Global and Country Analysis: Focus on Product, End User, and Region - Analysis and Forecast, 2022-2032 Yahoo Finance Read here
0 Replies | 1 Views
Protein Crystallization And Crystallography Market Size And Forecast To 2022 |Bruker Corporation, Rigaku Corporation, Hampton Research, Agilent Technologies, Corning Incorporated The Colby Echo News - The Colby Echo News
Sep 28, 2022 - 6:29 AM - by nmrlearner
nmrlearner's Avatar Protein Crystallization And Crystallography Market Size And Forecast To 2022 |Bruker Corporation, Rigaku Corporation, Hampton Research, Agilent Technologies, Corning Incorporated The Colby Echo News - The Colby Echo News

Protein Crystallization And Crystallography Market Size And Forecast To 2022 |Bruker Corporation, Rigaku Corporation, Hampton Research, Agilent Technologies, Corning Incorporated The Colby Echo News The Colby Echo News Read here
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[NMR paper] Probing the KRas Switch II Groove by Fluorine NMR Spectroscopy
Sep 28, 2022 - 6:29 AM - by nmrlearner
nmrlearner's Avatar Probing the KRas Switch II Groove by Fluorine NMR Spectroscopy

While there has been recent success in the development of KRas^(G12C) inhibitors, unmet needs for selective inhibitors of KRas^(G12D) and the remaining oncogenic KRas proteins remain. Here, we applied trifluoromethyl-containing ligands of KRas proteins as competitive probe ligands to assay the occupancy of the switch II pocket by ^(19)F NMR spectroscopy. Structure-activity-relationship studies of probe ligands increased the sensitivity of the assay and identified structures that differentially...

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[NMR paper] Investigating protein-excipient interactions of a multivalent VHH therapeutic protein using NMR spectroscopy
Sep 28, 2022 - 6:29 AM - by nmrlearner
nmrlearner's Avatar Investigating protein-excipient interactions of a multivalent VHH therapeutic protein using NMR spectroscopy

Fab Fragment antigen-binding; Fc Fragment crystallizable; HMW High molecular weight; ?HMW Difference between HMW species at stress temperature and 5C controls; IgG Immunoglobulin G; mAbs Monoclonal antibodies; MV-V(HH) Multivalent V(HH) molecule with the format aC-L(1)-aC-L(1)-aD; NMR Nuclear magnetic resonance; scFv Single-chain fragment variable; SEC Size-exclusion chromatography; V(HH) Variable domain of Heavy chain of Heavy chain-only antibody.

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[NMR paper] Binding of Glycans to the SARS CoV-2 Spike Protein, an Open Question: NMR Data on Binding Site Localization, Affinity, and Selectivity
Sep 27, 2022 - 5:49 AM - by nmrlearner
nmrlearner's Avatar Binding of Glycans to the SARS CoV-2 Spike Protein, an Open Question: NMR Data on Binding Site Localization, Affinity, and Selectivity

We have used NMR experiments to explore binding of selected glycans and glycomimetics to the SARS CoV-2 spike glycoprotein (S-protein) and to its receptor binding domain (RBD). STD NMR experiments confirm binding of sialoglycans to the S-protein of the prototypic Wuhan strain virus and yield dissociation constants in the mM range. The absence of STD effects for sialoglycans in the presence of the Omicron/BA.1 S-protein reflects a loss of binding as a result of S-protein evolution. Likewise, no...

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Paternal low protein diet perturbs inter-generational metabolic homeostasis in a tissue-specific manner in mice | Communications Biology - Nature.com
Sep 26, 2022 - 5:24 PM - by nmrlearner
nmrlearner's Avatar Paternal low protein diet perturbs inter-generational metabolic homeostasis in a tissue-specific manner in mice | Communications Biology - Nature.com

Paternal low protein diet perturbs inter-generational metabolic homeostasis in a tissue-specific manner in mice | Communications Biology Nature.com Read here
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